Reinher Pimentel-Domínguez
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Reinher Pimentel-Domínguez has a total of 13 co-authors. Here are the top co-authors by number of shared publications:
- Abraham Cisneros-Mejorado
Laboratorio de Neurofisiología Celular, Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Boulevard Juriquilla 3001, Querétaro 76230, QRO, Mexico
1 shared publication Abraham J. Cisneros-Mejorado
Instituto de Neurobiología, Laboratorio de Neurofisiología Celular, Universidad Nacional Autónoma de México (UNAM), Boulevard Juriquilla 3001, 76230 Querétaro, Mexico
1 shared publication- Alexis Bernardo Sabido-Barahona
Centro de Investigación Científica de Yucatán, Unidad de Materiales, Calle 43 No. 130 x 32 y 34, Colonia Chuburná de Hidalgo, Mérida 97205, Yucatán, Mexico
1 shared publication - Antònia Colom-Casasnovas
Laboratorio de Neurofisiología Celular, Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Boulevard Juriquilla 3001, Querétaro 76230, QRO, Mexico
1 shared publication - Claudia Vásquez-López
Departamento de Física, Universidad de Sonora, Encinas y Rosales, s/n., Hermosillo 83000, SON, Mexico
1 shared publication - Juan Valerio Cauich-Rodríguez
Centro de Investigación Científica de Yucatán, Unidad de Materiales, Calle 43 No. 130 por 32 y 34, Colonia Chuburná de Hidalgo, Mérida 97205, Yucatán, Mexico
1 shared publication
Latest Publications
- Open Access
Evaluation of 3D-Printed Thermoplastic Polyurethane Nerve Guidance Conduits
Fused deposition modeling (FDM) is an emerging trend for producing nerve guidance conduits (NGCs). This technique allows distinct designs and dimensions to mimic peripheral nerve architecture and promote nerve regeneration. In this study, commercially available TPU 90A and 95A filaments were used for the fabrication of hollow simple wall (non-porous), grooved and gyroid multichannel conduits. The segmented polyurethanes were identified as PBA-MDI-BO-based polyurethanes by 1H NMR, FTIR and Raman spectroscopy. Thermal analyses, such as DSC and TGA, demonstrated that both TPUs possess sufficient thermal stability to be processed safely under the printing conditions employed. Tensile mechanical tests accounted for their differences in hard segment content in agreement with the Shore A hardness. The measured elastic modulus, in particular, was within a range that may be advantageous for peripheral nerve repair. The gyroid multichannel design showed enhanced resistance to radial compression and highly interconnected internal structure that supported primary neural cell viability and preserved cellular functionality. Therefore, polyurethane-based nerve guidance conduits can be manufactured by FDM, rendering high printability, favorable mechanical performance without compromising biocompatibility.
Open AccessEvaluation of 3D-Printed Thermoplastic Polyurethane Nerve Guidance Conduits
Fused deposition modeling (FDM) is an emerging trend for producing nerve guidance conduits (NGCs). This technique allows distinct designs and dimensions to mimic peripheral nerve architecture and promote nerve regeneration. In this study, commercially available TPU 90A and 95A filaments were used for the fabrication of hollow simple wall (non-porous), grooved and gyroid multichannel conduits. The segmented polyurethanes were identified as PBA-MDI-BO-based polyurethanes by 1H NMR, FTIR and Raman spectroscopy. Thermal analyses, such as DSC and TGA, demonstrated that both TPUs possess sufficient thermal stability to be processed safely under the printing conditions employed. Tensile mechanical tests accounted for their differences in hard segment content in agreement with the Shore A hardness. The measured elastic modulus, in particular, was within a range that may be advantageous for peripheral nerve repair. The gyroid multichannel design showed enhanced resistance to radial compression and highly interconnected internal structure that supported primary neural cell viability and preserved cellular functionality. Therefore, polyurethane-based nerve guidance conduits can be manufactured by FDM, rendering high printability, favorable mechanical performance without compromising biocompatibility.