Guanglin Chen
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Guanglin Chen has a total of 16 co-authors. Here are the top co-authors by number of shared publications:
- Guodong Sun
Guangdong Provincial Key Laboratory of Spine and Spinal Cord Reconstruction, The Fifth Affiliated Hospital (Heyuan Shenhe People's Hospital), Jinan University, Heyuan 517000, China; Department of Materials Science and Engineering, Engineering Research Center of Artificial Organs and Materials, Jinan University, Guangzhou 510632, China
1 shared publication Haonan Li
Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, China
1 shared publication- Jianhao Sun
Department of Internal Medicine, Weifang Hospital of Traditional Chinese Medicine, Shandong Second Medical University, Weifang City, China
1 shared publication Jinmei Zhang
Department of Endocrinology, Weifang Hospital of Traditional Chinese Medicine, Shandong Second Medical University, Weifang, China
1 shared publicationMiao Ge
Department of Spinal Surgery, Weifang Hospital of Traditional Chinese Medicine, Shandong Second Medical University, Weifang, China
1 shared publicationMishan Wu
Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, China
1 shared publication
Latest Publications
- Open Access
- 1 August 2025
- Published by Springer Nature in Neurosurgical Review
- Vol. 48 (1) , 1-13
Comparative efficacy of one-hole split endoscope versus unilateral biportal endoscopy in the treatment of lumbar disc herniation: a retrospective analysis
Lumbar disc herniation (LDH) is a prevalent spinal disorder affecting 20–40% of the population. This study compared the clinical efficacy of two minimally invasive techniques, one-hole split endoscopy (OSE) and unilateral biportal endoscopy (UBE), for treating single-level LDH. A retrospective analysis of 217 patients (OSE: 118; UBE: 99) treated between April 2021 and January 2025 demonstrated that while both techniques were effective, OSE offered several advantages. Incision lengths were shorter in the OSE group (2.20 ± 0.33 cm vs. 2.91 ± 0.33 cm; p < 0.001), and fewer intraoperative fluoroscopy sessions were required (2.05 ± 0.21 vs. 2.59 ± 0.59; p < 0.001). Postoperative assessments revealed lower Oswestry Disability Index(ODI) scores (19.40 ± 2.81 vs. 20.87 ± 2.88; p = 0.003) and reduced visual analog scale(VAS) scores for low back pain (1.87 ± 0.68 vs. 2.24 ± 0.58; p = 0.002) in the OSE group at 7 days. The cross-sectional area of the multifidus muscle decreased less in OSE (104.71 ± 36.10) compared to UBE (268.85 ± 40.00; p < 0.001). Complication rates were similar, with no major adverse events such as infections or nerve injuries. The minimally invasive nature of OSE may contribute to improved patient outcomes and satisfaction. Further large-scale, long-term studies are warranted to validate these findings and assess the long-term efficacy of OSE in spinal surgery. Clinical trial number: Not applicable.
- 1 August 2025
- Published by Springer Nature in Neurosurgical Review
- Vol. 48 (1) , 1-13
Open AccessComparative efficacy of one-hole split endoscope versus unilateral biportal endoscopy in the treatment of lumbar disc herniation: a retrospective analysis
Lumbar disc herniation (LDH) is a prevalent spinal disorder affecting 20–40% of the population. This study compared the clinical efficacy of two minimally invasive techniques, one-hole split endoscopy (OSE) and unilateral biportal endoscopy (UBE), for treating single-level LDH. A retrospective analysis of 217 patients (OSE: 118; UBE: 99) treated between April 2021 and January 2025 demonstrated that while both techniques were effective, OSE offered several advantages. Incision lengths were shorter in the OSE group (2.20 ± 0.33 cm vs. 2.91 ± 0.33 cm; p < 0.001), and fewer intraoperative fluoroscopy sessions were required (2.05 ± 0.21 vs. 2.59 ± 0.59; p < 0.001). Postoperative assessments revealed lower Oswestry Disability Index(ODI) scores (19.40 ± 2.81 vs. 20.87 ± 2.88; p = 0.003) and reduced visual analog scale(VAS) scores for low back pain (1.87 ± 0.68 vs. 2.24 ± 0.58; p = 0.002) in the OSE group at 7 days. The cross-sectional area of the multifidus muscle decreased less in OSE (104.71 ± 36.10) compared to UBE (268.85 ± 40.00; p < 0.001). Complication rates were similar, with no major adverse events such as infections or nerve injuries. The minimally invasive nature of OSE may contribute to improved patient outcomes and satisfaction. Further large-scale, long-term studies are warranted to validate these findings and assess the long-term efficacy of OSE in spinal surgery. Clinical trial number: Not applicable.