Botagoz Issergepova
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Botagoz Issergepova has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Auyeskhan Dzhumabekov
Department of Science and Consulting, Kazakhstan’s Medical University “KSPH”, Almaty 050060, Kazakhstan
1 shared publication - Indira Karibayeva
Department of Health Policy and Community Health, Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, GA 30460, USA
1 shared publication - Maiya Taushanova
Department of Public Health and Healthcare with a Nursing Course, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan
1 shared publication - Neilya Aldasheva
Department of Science Management, Kazakh Eye Research Institute, Almaty 050012, Kazakhstan
1 shared publication - Yerzhan Kuanyshbekov
Department of Spinal Neurosurgery and Peripheral Nervous System Pathology, National Center for Neurosurgery, Astana 010000, Kazakhstan
1 shared publication - Zhansaya Sultanbayeva
Science Department, Kazakh Eye Research Institute, 050012 Almaty, Kazakhstan
1 shared publication
Latest Publications
- Open Access
A Systematic Review and Meta-Analysis of the Success Rate of the Primary Probing in Pediatric Patients with Congenital Nasolacrimal Duct Obstruction in Different Age Groups
Background: Primary probing of the nasolacrimal duct remains the first-line surgical intervention for congenital nasolacrimal duct obstruction (CNLDO) in infants and young children. However, age-dependent success rates have been less thoroughly investigated. This systematic review and meta-analysis aims to evaluate the age-related success rates of primary probing in children with CNLDO. Methods: Systematic literature searches were performed in PubMed, Web of Science, Scopus, ScienceDirect, and Google Scholar in May 2025. A random-effects model was applied to estimate the overall success rate, while sensitivity analyses and publication bias assessments were performed to explore sources of variability. All statistical analyses were carried out using the “meta” and “metafor” packages in RStudio. Results: This meta-analysis reveals age-stratified success rates of primary probing for CNLDO: the highest pooled success rate occurred in infants aged 0–6 months (90.67%, I2 = 81%, p < 0.01), with procedures under general anesthesia achieving 95.42% (I2 = 50%; p = 0.11) efficacy. Success rates remained favorable in the 6–12 month group (85.18%, I2 = 86%, p < 0.01 overall; 89.60% with general anesthesia) but declined progressively thereafter (82.34%, I2 = 78%, p < 0.01 at 12–24 months). While a modest rebound occurred in the 24–48 month group (85.33%, I2 = 69%, p < 0.01), the oldest cohort (48+ months) demonstrated markedly reduced efficacy (63.47%, I2 = 66%, p = 0.05), despite exclusive use of general anesthesia. Conclusion: Primary probing yields the most favorable outcomes when conducted before 12 months of age, particularly under general anesthesia. Nonetheless, the overall certainty of evidence is low—mainly due to variability across studies—which should be taken into account in clinical decision-making.
Open AccessA Systematic Review and Meta-Analysis of the Success Rate of the Primary Probing in Pediatric Patients with Congenital Nasolacrimal Duct Obstruction in Different Age Groups
Background: Primary probing of the nasolacrimal duct remains the first-line surgical intervention for congenital nasolacrimal duct obstruction (CNLDO) in infants and young children. However, age-dependent success rates have been less thoroughly investigated. This systematic review and meta-analysis aims to evaluate the age-related success rates of primary probing in children with CNLDO. Methods: Systematic literature searches were performed in PubMed, Web of Science, Scopus, ScienceDirect, and Google Scholar in May 2025. A random-effects model was applied to estimate the overall success rate, while sensitivity analyses and publication bias assessments were performed to explore sources of variability. All statistical analyses were carried out using the “meta” and “metafor” packages in RStudio. Results: This meta-analysis reveals age-stratified success rates of primary probing for CNLDO: the highest pooled success rate occurred in infants aged 0–6 months (90.67%, I2 = 81%, p < 0.01), with procedures under general anesthesia achieving 95.42% (I2 = 50%; p = 0.11) efficacy. Success rates remained favorable in the 6–12 month group (85.18%, I2 = 86%, p < 0.01 overall; 89.60% with general anesthesia) but declined progressively thereafter (82.34%, I2 = 78%, p < 0.01 at 12–24 months). While a modest rebound occurred in the 24–48 month group (85.33%, I2 = 69%, p < 0.01), the oldest cohort (48+ months) demonstrated markedly reduced efficacy (63.47%, I2 = 66%, p = 0.05), despite exclusive use of general anesthesia. Conclusion: Primary probing yields the most favorable outcomes when conducted before 12 months of age, particularly under general anesthesia. Nonetheless, the overall certainty of evidence is low—mainly due to variability across studies—which should be taken into account in clinical decision-making.