SNSho Nagai

Sho Nagai

*This is an algorithmically generated author record based on publicly available information.

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Sho Nagai has a total of 22 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Psychiatric nurses' clinical decision‐making for adults clinically judged to have childhood maltreatment‐related attachment difficulties: A qualitative study employing the steps for coding and theorization method

    by Sho Nagai, Emiko Shinozaki

    Aim: To describe how experienced psychiatric nurses notice, interpret, and respond to adult inpatients whom they clinically judge to have childhood maltreatment‐related attachment difficulties and to clarify the practical reasoning underlying these judgments. Methods: Eleven experienced psychiatric nurses from two private psychiatric hospitals in Japan were purposively sampled. Participant observation and semi‐structured interviews focused on care of adults clinically understood to have childhood maltreatment‐related attachment difficulties. Case identification relied on nurses' clinical judgment and routine team discussions or record information; no standardized attachment assessment or independent verification of childhood maltreatment history was used. Data were analyzed using the steps for coding and theorization (SCAT) method. Results: SCAT generated 54 themes or concepts organized into 10 categories and 24 subcategories. Nurses noticed recurrent relational patterns, including distrust, checking behavior, dependency‐aggression cycles, misinterpretation of staff intentions, self‐harm, and distress around proximity, and adjusted their responses to stabilize the patient–nurse dyad, avoid re‐traumatization, support emotional expression, and coordinate team care. Only a limited subset of subcategories was attachment‐specific; many others reflected broader psychiatric nursing practices applied through an attachment‐informed lens. A trauma‐focused noticing process was visible in nurses' attention to nonverbal cues and early behavioral change. Conclusions: The findings describe situated clinical reasoning rather than a new diagnostic technique or intervention model. Experienced psychiatric nurses adapted everyday psychiatric nursing practices to relational patterns they understood as childhood maltreatment‐related and attachment‐relevant. The model may inform education, supervision, and future patient‐inclusive research.

  • Top Cited Papers
    Open Access

    AI- vs Human-Based Assessment of Medical Interview Transcripts in a Generative AI–Simulated Patient System: Cross-Sectional Validation Study

    by Hiromizu Takahashi, Kiyoshi Shikino, Takeshi Kondo, Yuji Yamada, Yoshitaka Tomoda, Minoru Kishi, Yuki Aiyama, Sho Nagai, Akiko Enomoto, Yoshinori Tokushima, et al.

    Background: Generative artificial intelligence (AI) is increasingly used in medical education, including AI-based virtual patients to improve interview skills. However, how much AI-based assessment (ABA) differs from human-based assessment (HBA) remains unclear. Objective: This study aimed to compare the quality of clinical interview assessments generated via an ABA (GPT-o1 Pro [ABA-o1] and GPT-5 Pro [ABA-5]) with those generated via an HBA conducted by clinical instructors in an AI-based virtual patient setting. We also examined whether AI reduced evaluation time and assessed agreement across participants with different levels of clinical experience. Methods: A standardized case of leg weakness was implemented in an AI-based virtual patient. Seven participants (2 medical students, 3 residents, and 2 attending physicians) each conducted an interview with the AI patient, and transcripts were scored using the 25-item Master Interview Rating Scale (0‐125). Three evaluation strategies were compared. First, GPT-o1 Pro and GPT-5 Pro scored each transcript 5 times with different random seeds to test case specificity. Processing time was logged automatically. Second, 5 blinded clinical instructors independently rated each transcript once using the same rubric. Third, reliability metrics were applied. For AI, intraclass correlation coefficients (ICCs) quantified repeatability. For humans, the ICC(2,1) was calculated. Agreement was quantified using the Pearson r , Lin concordance correlation coefficient, Bland-Altman limits of agreement, Cronbach α, and ICC. Time efficiency was expressed as mean minutes per transcript and relative percentage reduction. Results: Mean interview scores were similar across methods (ABA-o1: mean 52.1, SD 6.9; ABA-5: mean 53.2, SD 6.8; HBA: mean 53.7, SD 6.8). Agreement between ABA and HBA was strong ( r =0.90; concordance correlation coefficient=0.88) with minimal bias (ABA-o1: mean 0.4, SD 2.7; ABA-5: mean 1.5, SD 5.2; limits of agreement: –4.9 to 5.7 for ABA-o1 and –8.6 to 11.7 for ABA-5). The Cronbach α was 0.81 (ABA-o1), 0.86 (ABA-5), and 0.80 (HBA); the ICC(3,1) was 0.77 (ABA-o1) and 0.82 (ABA-5); and the ICC(2,1) was 0.38 (HBA). The coefficient of variation for ABA was approximately half that of HBA (6.6% vs 13.9%). Processing time for 5 runs was 4 minutes, 19 seconds for ABA-o1 and 3 minutes, 20 seconds for ABA-5 vs 10 minutes, 16 seconds for physicians, corresponding to 58% and 67.6% reductions, respectively. Conclusions: ABA-o1 and ABA-5 produced scores closely matching HBA while demonstrating superior consistency and reliability. In the setting of virtual interview transcripts, these findings suggest that ABA may serve as a valid, rapid, and scalable alternative to HBA, reducing per-assessment time by over half. Applied strategically, AI-based scoring could enable timely feedback, improve efficiency, and reduce faculty workload. Further research is needed to confirm generalizability across broader settings.


  • Open Access

    Comparing AI- and Human-Based Assessments of Medical Interview Transcripts Using a Generative AI Simulated Patient System. (Preprint)

    by Hiromizu Takahashi, Kiyoshi Shikino, Takeshi Kondo, Yuji Yamada, Yoshitaka Tomoda, Minoru Kishi, Yuki Aiyama, Sho Nagai, Akiko Enomoto, Yoshinori Tokushima, et al.

    BACKGROUND Generative AI is increasingly used in medical education, including the use of AI-based virtual patients to improve interview skills. However, it remains unclear how much AI-based assessment (ABA) differs from those of Human-based assessment (HBA). OBJECTIVE This study aimed to compare the quality of clinical interview assessments generated by an ABA using a virtual patient with those provided by a HBA conducted by clinical instructors. Additionally, it evaluated whether the use of AI could lead to a measurable reduction in evaluation time, and examined the level of agreement across participants with differing levels of clinical experience. METHODS A standardized leg-weakness case was implemented in an AI based virtual patient. Seven participants—two medical students, three resident physicians, and two attending physicians—each conducted an interview, and transcripts were scored with the Master Interview Rating Scale (MIRS; 25 items, 0–5 scale; total 0–125). Two evaluation strategies were compared. (1) ChatGPT o1-Pro scored each transcript five times with different random seeds to assess case specificity; total runtime for the five scores was automatically logged. (2) Five blinded clinical instructors , after a preparatory webinar reviewing the rubric and practicing on sample transcripts, each rated every transcript once and recorded clock time per rating. Because the five AI outputs are replicates of the same algorithm, intraclass correlation coefficients (ICC) were used to quantify repeatability rather than inter rater reliability. For human raters, we calculated ICC (2,1). Mean scores from both methods were compared, and agreement was quantified with Pearson’s r, Lin’s concordance correlation coefficient (ρc), Bland–Altman limits of agreement (LoA), internal consistency (Cronbach’s α), and ICC. Time efficiency was expressed as mean minutes per transcript and the relative percentage reduction achieved by AI scoring. RESULTS Mean interview scores were similar for ABA and HBA (52.1 ± 6.9 vs 53.7 ± 6.8). Agreement was strong (r = 0.92; ρc = 0.92) with minimal bias (+0.4 points; LoA −4.9 to +5.7). ABA showed higher internal consistency (α = 0.936 vs 0.863) and greater inter rater reliability (ICC = 0.77 vs 0.38). The coefficient of variation for ABA scores was roughly half that of HBA scores (6.6 % vs 13.9 %). In addition, ChatGPT completed each five run analysis in 4.3 ± 1.7 minutes compared with 10.3 ± 3.3 minutes for physicians, representing a 58 % reduction in assessment time. CONCLUSIONS ABA scores that closely matched HBA scores while demonstrating superior consistency and reliability. In the setting of virtual clinical interview transcripts, these preliminary findings suggest that ABA shows potential as a valid, rapid, and scalable alternative to HBA. When applied strategically, it could potentially furnish timely formative feedback, quantify efficiency gains, and reduce faculty workload without compromising assessment quality. Further research is needed to determine whether this can be achieved without compromising assessment quality.