Alexandre Pariente
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Alexandre Pariente has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
Francine Etcharry
1 shared publicationMichel Biour
1 shared publicationSylvie Ferrari
1 shared publicationValérie Cales
1 shared publicationYves Laborde
1 shared publication
Latest Publications
- 1 July 2006
- Published by Wolters Kluwer Health in European Journal of Gastroenterology & Hepatology
- Vol. 18 (7) , 785-787
Imatinib mesylate-induced acute hepatitis in a patient treated for gastrointestinal stromal tumour
We report the first case of hepatocellular injury occurring in a patient treated for metastatic gastrointestinal stromal tumour (GIST) with imatinib mesylate, with two positive rechallenges including one with 2.5% of the current therapeutic dosage. The patient could be treated later with sunitinib without liver toxicity. Grade 3-4 liver toxicity could occur in one out of 40 treated patients with imatinib for GIST, and fatalities have been reported. Regular monitoring of liver function tests is essential in patients treated with imatinib.
- 1 July 2006
- Published by Wolters Kluwer Health in European Journal of Gastroenterology & Hepatology
- Vol. 18 (7) , 785-787
Imatinib mesylate-induced acute hepatitis in a patient treated for gastrointestinal stromal tumour
We report the first case of hepatocellular injury occurring in a patient treated for metastatic gastrointestinal stromal tumour (GIST) with imatinib mesylate, with two positive rechallenges including one with 2.5% of the current therapeutic dosage. The patient could be treated later with sunitinib without liver toxicity. Grade 3-4 liver toxicity could occur in one out of 40 treated patients with imatinib for GIST, and fatalities have been reported. Regular monitoring of liver function tests is essential in patients treated with imatinib.