Yuxin Sun
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Yuxin Sun has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Fengdan Wang
Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
1 shared publication - Hanze Du
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China
1 shared publication - Hui Pan
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China
1 shared publication - Shi Chen
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
1 shared publication - Xueqing Zheng
Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China
1 shared publication - Zhibo Zhou
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China
1 shared publication
Latest Publications
- 2 September 2025
- Published by Springer Nature in Pediatric Radiology
- Vol. 55 (12) , 2621-2631
Discordance between knee and hand-wrist bone age in adolescents: implications for skeletal maturity assessment and its association with thyroid-stimulating hormone levels
Background Hand-wrist radiographs may not fully reflect skeletal bone age (BA) during mid-to-late puberty. Knee magnetic resonance imaging (MRI), a non-radiative imaging technique, may provide detailed evaluation of the lower limbs. Objective To validate the San Diego MRI-based knee BA atlas in a Chinese adolescent cohort presenting with growth deceleration, evaluate the concordance between knee and hand-wrist BA, and explore factors influencing potential discrepancies. Materials and methods This study involved 227 adolescents. Hand-wrist BA was assessed using the Greulich and Pyle atlas with hand-wrist radiographs, and knee BA using the San Diego atlas with knee MRI. Correlations between knee BA, hand-wrist BA, and chronological age (CA) were analyzed. Discrepancies between the two sites were further evaluated for associated clinical factors. Results Knee BA correlated better with CA (rs = 0.816, P < 0.001) than with hand-wrist BA (rs = 0.763, P < 0.001). The mean difference between hand-wrist BA and CA was 1.08 ± 1.19 years, and between knee BA and CA was 0.71 ± 1.06 years (P < 0.001). 14.1% of adolescents showed more advanced knee maturity than hand-wrist bones. Thyroid-stimulating hormone (TSH) levels were positively associated with the difference between hand-wrist and knee BA (rs = -0.198, P = 0.011). Subclinical hypothyroidism significantly increased the risk of knee overmaturity (OR = 6.022, P < 0.001). Conclusion Knee MRI is a reliable imaging modality for assessing skeletal maturity in adolescents with growth retardation. A moderate correlation was observed between hand-wrist and knee BA. In adolescents with elevated TSH levels, knee MRI may be preferable to hand-wrist radiographs for predicting final height, evaluating growth potential, and guiding growth hormone therapy decisions. Graphical Abstract
- 2 September 2025
- Published by Springer Nature in Pediatric Radiology
- Vol. 55 (12) , 2621-2631
Discordance between knee and hand-wrist bone age in adolescents: implications for skeletal maturity assessment and its association with thyroid-stimulating hormone levels
Background Hand-wrist radiographs may not fully reflect skeletal bone age (BA) during mid-to-late puberty. Knee magnetic resonance imaging (MRI), a non-radiative imaging technique, may provide detailed evaluation of the lower limbs. Objective To validate the San Diego MRI-based knee BA atlas in a Chinese adolescent cohort presenting with growth deceleration, evaluate the concordance between knee and hand-wrist BA, and explore factors influencing potential discrepancies. Materials and methods This study involved 227 adolescents. Hand-wrist BA was assessed using the Greulich and Pyle atlas with hand-wrist radiographs, and knee BA using the San Diego atlas with knee MRI. Correlations between knee BA, hand-wrist BA, and chronological age (CA) were analyzed. Discrepancies between the two sites were further evaluated for associated clinical factors. Results Knee BA correlated better with CA (rs = 0.816, P < 0.001) than with hand-wrist BA (rs = 0.763, P < 0.001). The mean difference between hand-wrist BA and CA was 1.08 ± 1.19 years, and between knee BA and CA was 0.71 ± 1.06 years (P < 0.001). 14.1% of adolescents showed more advanced knee maturity than hand-wrist bones. Thyroid-stimulating hormone (TSH) levels were positively associated with the difference between hand-wrist and knee BA (rs = -0.198, P = 0.011). Subclinical hypothyroidism significantly increased the risk of knee overmaturity (OR = 6.022, P < 0.001). Conclusion Knee MRI is a reliable imaging modality for assessing skeletal maturity in adolescents with growth retardation. A moderate correlation was observed between hand-wrist and knee BA. In adolescents with elevated TSH levels, knee MRI may be preferable to hand-wrist radiographs for predicting final height, evaluating growth potential, and guiding growth hormone therapy decisions. Graphical Abstract