Carolina Perrone Marques
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Carolina Perrone Marques has a total of 17 co-authors. Here are the top co-authors by number of shared publications:
- Ana Carolina Pires de Rezende
Radiotherapy Department, Hospital Israelita Albert Einstein, São Paulo, Brazil
1 shared publication - Andreza Alice Feitosa Ribeiro
Hospital Israelita Albert Einstein, Bone Marrow Transplantation Unit, Sao Paulo, Brazil
1 shared publication - Carla Juliana Ribas
Universidade do Vale do Itajaí
1 shared publication - Daniel Cury Ogata
Universidade do Vale do Itajaí
1 shared publication - Eduardo Weltman
Radiotherapy Department, Hospital Israelita Albert Einstein, São Paulo, Brazil
1 shared publication Fangio Ferrari
Universidade do Vale do Itajaí (UNIVALI)
1 shared publication
Latest Publications
- Open Access
- 30 July 2026
- Published by Springer Nature in Current Tissue Microenvironment Reports
- Vol. 7 (1) , 7
Total marrow irradiation-based, reduced-intensity conditioning regimen for elderly patients undergoing hematopoietic cell transplantation for hematological malignancies
Background: Elderly patients are increasingly being offered allogeneic hematopoietic cell transplantation (HCT), and several strategies have been developed to meet their needs. The objective of the current study was to report the feasibility of a reduced-intensity busulfan/fludarabine conditioning regimen with total marrow irradiation in older patients. Methods: This single-center study included 28 patients aged 60–77 years with a median follow-up of 34 months. Results: Overall survival at 2 years was 46%, relapse rate was 30%, and non-relapse mortality was 23%, yielding a progression-free survival of 46%. Rates of grades II-IV acute GVHD, III-IV acute GVHD, and chronic GVHD were 47%, 8%, and 19%, respectively. Only one patient did not achieve neutrophil engraftment. Three patients experienced sinusoidal obstruction syndrome, and all recovered. Causes of death included disease progression ( n = 10), infection ( n = 5, including one COVID-19 case), and acute myocardial infarction ( n = 1). Conclusion: Our results demonstrate the feasibility of an intensified, total marrow irradiation-based conditioning regimen in an elderly cohort, primarily comprising transplants from alternative donors for high-risk diseases. Non-relapse mortality was very low, given the patients’ profile, and compares favorably with others reports reduced-intensity regimen with total body irradiation in older patients. Future studies should compare it to the standard reduced-intensity and non-myeloablative regimens.
- 30 July 2026
- Published by Springer Nature in Current Tissue Microenvironment Reports
- Vol. 7 (1) , 7
Open AccessTotal marrow irradiation-based, reduced-intensity conditioning regimen for elderly patients undergoing hematopoietic cell transplantation for hematological malignancies
Background: Elderly patients are increasingly being offered allogeneic hematopoietic cell transplantation (HCT), and several strategies have been developed to meet their needs. The objective of the current study was to report the feasibility of a reduced-intensity busulfan/fludarabine conditioning regimen with total marrow irradiation in older patients. Methods: This single-center study included 28 patients aged 60–77 years with a median follow-up of 34 months. Results: Overall survival at 2 years was 46%, relapse rate was 30%, and non-relapse mortality was 23%, yielding a progression-free survival of 46%. Rates of grades II-IV acute GVHD, III-IV acute GVHD, and chronic GVHD were 47%, 8%, and 19%, respectively. Only one patient did not achieve neutrophil engraftment. Three patients experienced sinusoidal obstruction syndrome, and all recovered. Causes of death included disease progression ( n = 10), infection ( n = 5, including one COVID-19 case), and acute myocardial infarction ( n = 1). Conclusion: Our results demonstrate the feasibility of an intensified, total marrow irradiation-based conditioning regimen in an elderly cohort, primarily comprising transplants from alternative donors for high-risk diseases. Non-relapse mortality was very low, given the patients’ profile, and compares favorably with others reports reduced-intensity regimen with total body irradiation in older patients. Future studies should compare it to the standard reduced-intensity and non-myeloablative regimens.
- Open Access
- 1 June 2018
- Published by Associação Catarinense de Medicina in Arquivos Catarinenses de Medicina
- Vol. 47 (2) , 231-236
ESTRONGILOIDÍASE GÁSTRICA EM PACIENTE IMUNOCOMPETENTE - RELATO DE CASO.
A estrongiloidíase humana é um tipo de helmintose causada por duas espécies de nematoides intestinais pertencentes ao gênero Strongyloides. O acometimento do estômago é raro, especialmente em imunocompetentes, e quando acontece os principais sintomas gastrointestinais incluem diarreia, desconforto abdominal, náusea e anorexia. O exame anatomopatológico a partir de biópsias fornece o diagnóstico definitivo. O objetivo deste trabalho é relatar um caso atípico de estrongiloidíase gástrica em paciente imunocompetente que apresentava quadro de dor abdominal difusa recorrente.
- 1 June 2018
- Published by Associação Catarinense de Medicina in Arquivos Catarinenses de Medicina
- Vol. 47 (2) , 231-236
Open AccessESTRONGILOIDÍASE GÁSTRICA EM PACIENTE IMUNOCOMPETENTE - RELATO DE CASO.
A estrongiloidíase humana é um tipo de helmintose causada por duas espécies de nematoides intestinais pertencentes ao gênero Strongyloides. O acometimento do estômago é raro, especialmente em imunocompetentes, e quando acontece os principais sintomas gastrointestinais incluem diarreia, desconforto abdominal, náusea e anorexia. O exame anatomopatológico a partir de biópsias fornece o diagnóstico definitivo. O objetivo deste trabalho é relatar um caso atípico de estrongiloidíase gástrica em paciente imunocompetente que apresentava quadro de dor abdominal difusa recorrente.