Christos Chachopoulos
Research Subjects
Research Interests
Christos Chachopoulos has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Anna Voulgari
Statistician, ASTAT Statistical Agency, Glyfada, Greece, Greece
1 shared publication - Chrysostomos Kalantzis
Department of Gastroenterology, 417 Army Equity Fund Hospital (NIMTS), Athens, Greece, Greece
1 shared publication Evie- Maria Delicha
Statistician, ASTAT Statistical Agency, Glyfada, Greece, Greece
1 shared publication- Foteini Leventaki
Department of Gastroenterology, 417 Army Equity Fund Hospital (NIMTS), Athens, Greece., Greece
1 shared publication - Ioannis Braimakis
1)Translational Gastroenterology and Liver Unit, John Radcliffe Hospital, Oxford University Hospitals, Oxford, UK. 2)Fellow of the Hellenic Society of Gastroenterology, UK
1 shared publication - Ioannis Stasinos
Department of Gastroenterology, 417 Army Equity Fund Hospital (NIMTS), 11528 Athens, Greece
1 shared publication
Latest Publications
- Open Access
- 3 October 2025
- Published by MDPI AG in Preprints.org
A Comparative Study on Colorectal Neoplasia Detection Rates in Average-Risk Individuals Under 50 Years of Age
Background/Objectives: Colonoscopy, as the modality of choice for Colorectal cancer (CRC) screening, has a well-documented impact on decreasing CRC incidence. Although starting CRC screening at the age of 50 for average-risk individuals is widely recommended, several studies suggest the need for an earlier onset. Methods: Study of 353 average-risk individuals aged 40-54 years old who underwent colonoscopy investigation. Out of the study population, 3 age groups (40-44, 45-49, and 50-54 years old) were formed. Adenoma detection rate (ADR), polyp detection rate (PDR), sessile serrated lesions detection rate (SDR), and rate of advanced colorectal neoplasia (ACRN) and colorectal cancer (CRC) were compared between the groups. Results: Comparing age groups 40-44 vs. 50-54 years old we found a statistically significant difference in terms of PDR and ADR (p-value= 0.038 and 0.045 respectively). On the contrary, no statistically significant difference was found between the age groups 45-49 and 50-54 years old, in terms of PDR, ADR, SDR, and CRC detection rate (p-value= 0.063 for PDR, 0.2 for ADR, 0.3 for SDR, >0.9 for CRC). ACRN rates were comparable between the age groups 45-49 and 50-54 years old. As for patients’ gender, males 50-54 had increased ADR and PDR in comparison with groups 40-44 and 45-49. In contrast, females bared no statistically significant difference in terms of ADR and PDR in all groups. Conclusions: Age group 45-49, sharing comparable detection rates with group 50-54, could also be considered for colorectal cancer screening.
- 3 October 2025
- Published by MDPI AG in Preprints.org
Open AccessA Comparative Study on Colorectal Neoplasia Detection Rates in Average-Risk Individuals Under 50 Years of Age
Background/Objectives: Colonoscopy, as the modality of choice for Colorectal cancer (CRC) screening, has a well-documented impact on decreasing CRC incidence. Although starting CRC screening at the age of 50 for average-risk individuals is widely recommended, several studies suggest the need for an earlier onset. Methods: Study of 353 average-risk individuals aged 40-54 years old who underwent colonoscopy investigation. Out of the study population, 3 age groups (40-44, 45-49, and 50-54 years old) were formed. Adenoma detection rate (ADR), polyp detection rate (PDR), sessile serrated lesions detection rate (SDR), and rate of advanced colorectal neoplasia (ACRN) and colorectal cancer (CRC) were compared between the groups. Results: Comparing age groups 40-44 vs. 50-54 years old we found a statistically significant difference in terms of PDR and ADR (p-value= 0.038 and 0.045 respectively). On the contrary, no statistically significant difference was found between the age groups 45-49 and 50-54 years old, in terms of PDR, ADR, SDR, and CRC detection rate (p-value= 0.063 for PDR, 0.2 for ADR, 0.3 for SDR, >0.9 for CRC). ACRN rates were comparable between the age groups 45-49 and 50-54 years old. As for patients’ gender, males 50-54 had increased ADR and PDR in comparison with groups 40-44 and 45-49. In contrast, females bared no statistically significant difference in terms of ADR and PDR in all groups. Conclusions: Age group 45-49, sharing comparable detection rates with group 50-54, could also be considered for colorectal cancer screening.