Raphaela Carvalho Silva

Objective: This study aimed to analyze the effects of multiprofessional cooperation in the administration of high-complexity medications in hospital units, seeking to understand how this interaction impacts patient safety and therapeutic efficacy. Theoretical Framework: The research was based on studies addressing the administration of critical drugs, the risks associated with the medication chain, and the benefits of joint action among health professionals. The main authors discuss the importance of standardized protocols and interprofessional communication to mitigate adverse events. Method: This is an integrative literature review, composed of 20 articles selected from databases such as SciELO, LILACS, MEDLINE/PubMed, and BDENF, using inclusion criteria such as articles with results pertinent to the research goals, publications in Portuguese, English, and Spanish, and no more than 10 years old. Results and Discussion: The findings indicate that the articulated action among healthcare professionals significantly contributes to medication safety, especially in high-pressure clinical contexts. The active presence of the pharmacist and the strategic role of nursing were pointed out as essential to reduce errors in drug administration. Research Implications: The study highlights the need for institutional policies that encourage interprofessional practice, the standardization of protocols, and continued education, contributing to safer and more effective care. Originality/Value: By integrating scientific evidence and collaborative practices, the study provides a relevant contribution to hospital care management, reinforcing the value of multiprofessional cooperation in the administration of high-complexity medications.