Zeinab Dehghani

Skin color has historically been a focal point of discrimination, yet fairness research in machine learning for medical imaging often relies on coarse subgroup categories, overlooking individual-level variations. Such group-based approaches risk obscuring biases faced by outliers within subgroups. This study introduces a distribution-based framework for evaluating and mitigating individual fairness in skin lesion classification. We treat skin tone as a continuous attribute rather than a categorical label, and employ kernel density estimation (KDE) to model its distribution. We further compare twelve statistical distance metrics to quantify disparities between skin tone distributions and propose a distance-based reweighting (DRW) loss function to correct underrepresentation in minority tones. Experiments across CNN and Transformer models demonstrate: (i) the limitations of categorical reweighting in capturing individual-level disparities, and (ii) the superior performance of distribution-based reweighting, particularly with Fidelity Similarity (FS), Wasserstein Distance (WD), Hellinger Metric (HM), and Harmonic Mean Similarity (HS). These findings establish a robust methodology for advancing fairness at individual level in dermatological AI systems, and highlight broader implications for sensitive continuous attributes in medical image analysis.

Generative AI, such as Large Language Models (LLMs), has achieved impressive progress but still produces hallucinations and unverifiable claims, limiting reliability in sensitive domains. Retrieval-Augmented Generation (RAG) improves accuracy by grounding outputs in external knowledge, especially in domains like healthcare, where precision is vital. However, RAG remains opaque and essentially a black box, heavily dependent on data quality. We developed a method-agnostic, perturbation-based framework that provides token and component-level interoperability for Graph RAG using SMILE and named it as Knowledge-Graph (KG)-SMILE. By applying controlled perturbations, computing similarities, and training weighted linear surrogates, KG-SMILE identifies the graph entities and relations most influential to generated outputs, thereby making RAG more transparent. We evaluate KG-SMILE using comprehensive attribution metrics, including fidelity, faithfulness, consistency, stability, and accuracy. Our findings show that KG-SMILE produces stable, human-aligned explanations, demonstrating its capacity to balance model effectiveness with interpretability and thereby fostering greater transparency and trust in machine learning technologies.