Rixin Guo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Rixin Guo has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Feng Wei
Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China
1 shared publication - Hongmei Yang
Public Experimental Center, Changchun University of Chinese Medicine, Changchun 130117, China
1 shared publication - Jing Liu
National Institutes for Food and Drug Control, Beijing 100050, China
1 shared publication - Weiyin Xu
National Institutes for Food and Drug Control, Beijing 100050, China
1 shared publication - Yanan Zhou
National Institutes for Food and Drug Control, Beijing 100050, China
1 shared publication - Yongqiang Lin
Institute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control
1 shared publication
Latest Publications
- Open Access
Potential of Traditional Chinese Medicine Brucea javanica in Cancer Treatment: A Review of Chemical Constituents, Pharmacology, and Clinical Applications
Brucea javanica (BJ), a key representative of traditional Chinese herbal medicine, is derived from the dried mature fruit of Brucea javanica (L.) Merr., a plant in the Simaroubaceae family. Its pharmacological activity is largely attributed to diverse chemical constituents. To date, approximately 200 distinct chemical constituents have been isolated and identified, mainly comprising quassinoids, triterpenes, alkaloids, steroids, phenylpropanoids, and flavonoids. Contemporary pharmacological studies have demonstrated the significant activities of BJ in various areas, including anti-tumor, anti-inflammatory, and anti-parasitic effects. Notably, its oil form (Brucea javanica oil) has been extensively utilized in treating various cancer types. This review aims to systematically summarize the antitumor components, mechanisms of action, and clinical applications in cancer therapy, with the goal of providing theoretical support for further antitumor research and the development of new BJ-based drugs, highlighting its potential as an antitumor agent.
Open AccessPotential of Traditional Chinese Medicine Brucea javanica in Cancer Treatment: A Review of Chemical Constituents, Pharmacology, and Clinical Applications
Brucea javanica (BJ), a key representative of traditional Chinese herbal medicine, is derived from the dried mature fruit of Brucea javanica (L.) Merr., a plant in the Simaroubaceae family. Its pharmacological activity is largely attributed to diverse chemical constituents. To date, approximately 200 distinct chemical constituents have been isolated and identified, mainly comprising quassinoids, triterpenes, alkaloids, steroids, phenylpropanoids, and flavonoids. Contemporary pharmacological studies have demonstrated the significant activities of BJ in various areas, including anti-tumor, anti-inflammatory, and anti-parasitic effects. Notably, its oil form (Brucea javanica oil) has been extensively utilized in treating various cancer types. This review aims to systematically summarize the antitumor components, mechanisms of action, and clinical applications in cancer therapy, with the goal of providing theoretical support for further antitumor research and the development of new BJ-based drugs, highlighting its potential as an antitumor agent.