Jaswinder Singh Maras
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Jaswinder Singh Maras has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Bikrant Bihari Lal
Department of Pediatric Hepatology Institute of Liver and Biliary Sciences New Delhi India
1 shared publication - Neha Sharma
Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India
1 shared publication - Rajeev Khanna
Department of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India
1 shared publication - Seema Alam
Department of Pediatric Hepatology Institute of Liver and Biliary Sciences New Delhi India
1 shared publication - Tamoghna Biswas
Department of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India
1 shared publication - Vikas Kohli
Pediatric Cardiology and Congenital Cardiac Surgery Unit, Indraprastha Apollo Hospital, New Delhi, India
1 shared publication
Latest Publications
- 18 October 2025
- Published by Springer Nature in Hepatology International
- Vol. 20 (2) , 419-427
Cirrhotic cardiomyopathy in children with biliary atresia and genetic intrahepatic cholestasis: clinical course and outcomes
Objectives Cirrhotic cardiomyopathy (CCM) is an under recognized entity in children. The present study aimed to explore the prevalence and natural history of CCM and its impact on outcomes among children with biliary atresia (BA) and genetic intrahepatic cholestasis (GIC). Methods This was a prospective observational study. All children aged 0–18 years and diagnosed with either BA or GIC were included. Relevant clinical and biochemical parameters were recorded and transthoracic echocardiography was done. Left ventricular mass index (LVMI) ≥ 95 g/m2.7 and/or relative wall thickness of left ventricle ≥ 0.42 was used for defining CCM. Results Eighty nine children were included in the study, 64 with BA and 25 with GIC. Prevalence of CCM in children with BA and GIC were 53.13% and 48% respectively. LVMI (g/m2.7) was significantly higher in children with unsuccessful KPE (p = 0.05 and p = 0.024) and unoperated BA (p < 0.001 and p = 0.002) compared to those with successful KPE and GIC. Serum bile acid levels were significantly (p = 0.026) higher among children with CCM. CCM was associated with a lower native liver survival (NLS) (p = 0.0039) and overall survival (OS) (p = 0.006) at 12 months. There were no significant associations between presence of CCM and post-LT mortality, time to extubation, duration of inotrope requirement or length of ICU stay. 80% children with CCM at baseline had resolution of CCM within 6 months post-LT. Conclusions CCM is prevalent in almost half of patients with BA and GIC and is associated with decreased NLS and OS. Serum bile acids were significantly higher in children with CCM.
- 18 October 2025
- Published by Springer Nature in Hepatology International
- Vol. 20 (2) , 419-427
Cirrhotic cardiomyopathy in children with biliary atresia and genetic intrahepatic cholestasis: clinical course and outcomes
Objectives Cirrhotic cardiomyopathy (CCM) is an under recognized entity in children. The present study aimed to explore the prevalence and natural history of CCM and its impact on outcomes among children with biliary atresia (BA) and genetic intrahepatic cholestasis (GIC). Methods This was a prospective observational study. All children aged 0–18 years and diagnosed with either BA or GIC were included. Relevant clinical and biochemical parameters were recorded and transthoracic echocardiography was done. Left ventricular mass index (LVMI) ≥ 95 g/m2.7 and/or relative wall thickness of left ventricle ≥ 0.42 was used for defining CCM. Results Eighty nine children were included in the study, 64 with BA and 25 with GIC. Prevalence of CCM in children with BA and GIC were 53.13% and 48% respectively. LVMI (g/m2.7) was significantly higher in children with unsuccessful KPE (p = 0.05 and p = 0.024) and unoperated BA (p < 0.001 and p = 0.002) compared to those with successful KPE and GIC. Serum bile acid levels were significantly (p = 0.026) higher among children with CCM. CCM was associated with a lower native liver survival (NLS) (p = 0.0039) and overall survival (OS) (p = 0.006) at 12 months. There were no significant associations between presence of CCM and post-LT mortality, time to extubation, duration of inotrope requirement or length of ICU stay. 80% children with CCM at baseline had resolution of CCM within 6 months post-LT. Conclusions CCM is prevalent in almost half of patients with BA and GIC and is associated with decreased NLS and OS. Serum bile acids were significantly higher in children with CCM.