Qin-Yang He
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Qin-Yang He has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Jie Peng
Engineering Research Center of Polyploidy Fish Reproduction and Breeding of the State Education Ministry, College of Life Science, Hunan Normal University, Changsha 410081, China
1 shared publication - Mingzhu Huang
School of Life Science, Jiangxi Normal University, Nanchang 330022, China; National R&D Center of Freshwater Fish Processing, Jiangxi Normal University, Nanchang 330022, China
1 shared publication - Sheng-Wei Luo
Engineering Research Center of Polyploidy Fish Reproduction and Breeding of the State Education Ministry, College of Life Science, Hunan Normal University, Changsha, 410081, PR China
1 shared publication - Xu-Ying Kuang
Engineering Research Center of Polyploidy Fish Reproduction and Breeding of the State Education Ministry, College of Life Science, Hunan Normal University, Changsha 410081, China
1 shared publication - Yude Wang
Engineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, Hunan Normal University, Changsha 410081, China
1 shared publication - Zhuangwen Mao
Hunan Provincial Key Laboratory of Nutrition and Quality Control of Aquatic Animals, Department of Biological and Environmental Engineering, Changsha University, Changsha 410022, China
1 shared publication
Latest Publications
- Open Access
Triploid Cyprinid Fish (TCF) Under Aeromonas sp. AS1-4 Infection: Metabolite Characteristics and In Vitro Assessment of Probiotic Potentials of Intestinal Enterobacter Strains
The majority of Aeromonas strains are opportunistic pathogens for both humans and animals, causing a variety of diseases and posing a considerable risk to their health. In the current study, triploid cyprinid fish (TCF) were infected with a novel pathogenic Aeromonas sp. AS1-4 for pathological analysis. TCFs receiving Aeromonas sp. AS1-4 challenge exhibited oxidative damage in the liver and spleen, along with significant changes in immune-related gene expressions. Metabolomics assay indicated that strain AS1-4 challenge may exhibit a significant impact on metabolic processes of amino acids, with methylsuccinic acid (MSA) identified as vital biomarker. Following that, three potential probiotics designated Enterobacter strains fkY27-2, fkY84-1 and fkY84-4 were isolated from the intestine of TCFs, displaying excellent safety characteristics. In addition, intestinal Enterobacter strains exhibited multiple probiotic traits, including high degrees of hydrophobic activity, aggregation performance, biofilm-forming activity (BFA) and nutrient decomposing ability. Moreover, these probiotic isolates markedly coaggregated with Aeromonas sp. AS1-4 and Edwardsiella tarda 1l-4 and then suppressed their pathogenic biofilm-forming abilities, along with possessing robust antioxidant potential against various free radicals. These findings may provide valuable insights into metabolic response in fish post infection and health management in aquaculture.
Open AccessTriploid Cyprinid Fish (TCF) Under Aeromonas sp. AS1-4 Infection: Metabolite Characteristics and In Vitro Assessment of Probiotic Potentials of Intestinal Enterobacter Strains
The majority of Aeromonas strains are opportunistic pathogens for both humans and animals, causing a variety of diseases and posing a considerable risk to their health. In the current study, triploid cyprinid fish (TCF) were infected with a novel pathogenic Aeromonas sp. AS1-4 for pathological analysis. TCFs receiving Aeromonas sp. AS1-4 challenge exhibited oxidative damage in the liver and spleen, along with significant changes in immune-related gene expressions. Metabolomics assay indicated that strain AS1-4 challenge may exhibit a significant impact on metabolic processes of amino acids, with methylsuccinic acid (MSA) identified as vital biomarker. Following that, three potential probiotics designated Enterobacter strains fkY27-2, fkY84-1 and fkY84-4 were isolated from the intestine of TCFs, displaying excellent safety characteristics. In addition, intestinal Enterobacter strains exhibited multiple probiotic traits, including high degrees of hydrophobic activity, aggregation performance, biofilm-forming activity (BFA) and nutrient decomposing ability. Moreover, these probiotic isolates markedly coaggregated with Aeromonas sp. AS1-4 and Edwardsiella tarda 1l-4 and then suppressed their pathogenic biofilm-forming abilities, along with possessing robust antioxidant potential against various free radicals. These findings may provide valuable insights into metabolic response in fish post infection and health management in aquaculture.