Han Gao
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Han Gao has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Hongsheng Gao
School of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou 225009, China
1 shared publication - Qijia Chen
Institute of Modern Horticulture Industry Technology, Yangzhou University, Yangzhou 225009, China
1 shared publication - Shen Chen
School of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou 225009, China
1 shared publication - Weiwen Wu
Institute of Modern Horticulture Industry Technology, Yangzhou University, Yangzhou 225009, China
1 shared publication - Yu Cheng
School of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou 225009, China
1 shared publication
Latest Publications
- Open Access
Transcriptomic and Metabolomic Analysis Reveals the Role of Exogenous GA3 in Regulating Strawberry Fruit Development via Auxin Signaling
Gibberellins (GAs) are pivotal phytohormones regulating fruit development, yet the molecular mechanisms by which they modulate strawberry fruit size and quality remain elusive. Here, we investigated the effects of exogenous GA3 on the fruit development of the cultivated strawberry (Fragaria × ananassa ‘Benihoppe’). Treatment with 20 mg/L GA3 significantly promoted fruit enlargement, advanced ripening by 7 days, and increased fruit weight and dimensions. Integrated transcriptomic and targeted metabolomic analyses revealed that GA3 application induced a substantial reprogramming of the endogenous hormone landscape, notably triggering a significant increase in auxin (IAA) levels. Transcriptome profiling identified numerous differentially expressed genes (DEGs), with KEGG enrichment analysis highlighting the “plant hormone signal transduction” pathway as the most significantly enriched. Further analysis pinpointed key DEGs involved in auxin signaling (AUX/IAA, ARF, GH3, and SAUR) and gibberellin perception (GID1), suggesting a central role for auxin-mediated processes in GA3-induced fruit expansion. We propose that exogenous GA3 promotes strawberry fruit development through a synergistic mechanism: (1) enhancing the biosynthesis of endogenous bioactive GAs; (2) activating auxin signal transduction pathways to drive cell expansion; and (3) attenuating the repression of DELLA proteins. Our study unveils the critical role of the GA3-IAA signaling axis in strawberry fruit development, providing a theoretical foundation for harnessing hormone regulation to improve fruit yield and quality in strawberry production.
Open AccessTranscriptomic and Metabolomic Analysis Reveals the Role of Exogenous GA3 in Regulating Strawberry Fruit Development via Auxin Signaling
Gibberellins (GAs) are pivotal phytohormones regulating fruit development, yet the molecular mechanisms by which they modulate strawberry fruit size and quality remain elusive. Here, we investigated the effects of exogenous GA3 on the fruit development of the cultivated strawberry (Fragaria × ananassa ‘Benihoppe’). Treatment with 20 mg/L GA3 significantly promoted fruit enlargement, advanced ripening by 7 days, and increased fruit weight and dimensions. Integrated transcriptomic and targeted metabolomic analyses revealed that GA3 application induced a substantial reprogramming of the endogenous hormone landscape, notably triggering a significant increase in auxin (IAA) levels. Transcriptome profiling identified numerous differentially expressed genes (DEGs), with KEGG enrichment analysis highlighting the “plant hormone signal transduction” pathway as the most significantly enriched. Further analysis pinpointed key DEGs involved in auxin signaling (AUX/IAA, ARF, GH3, and SAUR) and gibberellin perception (GID1), suggesting a central role for auxin-mediated processes in GA3-induced fruit expansion. We propose that exogenous GA3 promotes strawberry fruit development through a synergistic mechanism: (1) enhancing the biosynthesis of endogenous bioactive GAs; (2) activating auxin signal transduction pathways to drive cell expansion; and (3) attenuating the repression of DELLA proteins. Our study unveils the critical role of the GA3-IAA signaling axis in strawberry fruit development, providing a theoretical foundation for harnessing hormone regulation to improve fruit yield and quality in strawberry production.