Anurag N. Paranjape
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Anurag N. Paranjape has a total of 2 co-authors. Here are the top co-authors by number of shared publications:
- Flordeliza S. Villanueva
Center for Ultrasound Molecular Imaging and Therapeutics, Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA
1 shared publication - Xucai Chen
Center for Ultrasound Molecular Imaging and Therapeutics, Heart and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
1 shared publication
Latest Publications
- 14 November 2025
- Published by Springer Nature in Current Cardiology Reports
- Vol. 27 (1) , 155
Alteration of Essential Cell Function by Ultrasound-Targeted Microbubble Cavitation
Purpose of Review Ultrasound-targeted microbubble cavitation (UTMC) has emerged as a transformative non-invasive technology in diagnostic imaging, therapy, and targeted gene and drug delivery. As UTMC advances toward clinical translation, understanding its impact on fundamental cellular functions is essential. Recent Findings Recent studies on UTMC have provided insights into its effects on biological processes. These include transient membrane opening and resealing (sonoporation), calcium ion (Ca2+) influx, generation of free radicals, nitric oxide synthesis, cytoskeletal remodeling, inter-endothelial gap formation, gene expression changes, and neuroinflammation. Summary This review explores the mechanisms underlying UTMC, with a focus on ultrasound-targeted microbubble cavitation and its bioeffects on cellular function. We examine the molecular processes induced by cavitation, including sonoporation and Ca2+ influx, and highlight their effects on key biological processes.
- 14 November 2025
- Published by Springer Nature in Current Cardiology Reports
- Vol. 27 (1) , 155
Alteration of Essential Cell Function by Ultrasound-Targeted Microbubble Cavitation
Purpose of Review Ultrasound-targeted microbubble cavitation (UTMC) has emerged as a transformative non-invasive technology in diagnostic imaging, therapy, and targeted gene and drug delivery. As UTMC advances toward clinical translation, understanding its impact on fundamental cellular functions is essential. Recent Findings Recent studies on UTMC have provided insights into its effects on biological processes. These include transient membrane opening and resealing (sonoporation), calcium ion (Ca2+) influx, generation of free radicals, nitric oxide synthesis, cytoskeletal remodeling, inter-endothelial gap formation, gene expression changes, and neuroinflammation. Summary This review explores the mechanisms underlying UTMC, with a focus on ultrasound-targeted microbubble cavitation and its bioeffects on cellular function. We examine the molecular processes induced by cavitation, including sonoporation and Ca2+ influx, and highlight their effects on key biological processes.