ATAtikah

Atikah

*This is an algorithmically generated author record based on publicly available information.

Atikah has a total of 8 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    The Differences in Survival Rate, Motility, Morphology, and Viability of Male Spermatozoa with Severe Oligozoospermia in Cryopreservation Using Tip-micro and Micro-straw

    by Muhammad Fadhli Abdullah, Dimas Harditya Mulya Putra, Ria Margiana, Ninik Darsini, Petrus Supardi, Maria Paulina Budyandini Dyah Pramesti, Reny I’TIshom, Atikah, Syed Baharom Syed Ahmad Fuad

    Introduction: Cryopreservation of spermatozoa is a vital fertility preservation strategy for men with severe oligozoospermia, who face a substantial risk of azoospermia on the day of ovum pick-up. As a consensus on the optimal micro-volume carrier for these challenging cases remains elusive, this study was designed to compare the efficacy of two carriers, the tip-micro and the micro-straw, for cryopreserving severely oligozoospermic samples. Methods: In this experimental study, semen samples from 12 men with severe oligozoospermia were collected. All the samples were cryopreserved using a vapor fast-freezing method and divided between tip-micro and micro-straw carriers. Key sperm parameters motility, viability, and morphology were meticulously analyzed before freezing and after thawing to determine postthaw quality and survival rates. Results: Comparative analysis revealed no statistically significant differences in postthaw survival rate (54.33% ± 9.87% for tip-micro vs. 48.83% ± 9.95% for micro-straw), total motility (18.83% ± 4.68% vs. 17.33% ± 4.65%), or normal morphology (median 0% for both; all P > 0.05). However, a significant advantage was observed for the tip-micro in preserving sperm viability, which was markedly higher than in the micro-straw group (22.67% ± 4.73% vs. 19.92% ± 4.66%; P = 0.011). Conclusions: Both tip-micro and micro-straw carriers are effective for cryopreserving severely oligozoospermic samples. However, the tip-micro demonstrates superiority in maintaining sperm viability, likely due to a reduction in procedural mechanical stress. Given this advantage and its operational simplicity, the tip-micro represents a preferable clinical option for these cases.