AWAlysha D. Wira

Alysha D. Wira

*This is an algorithmically generated author record based on publicly available information.

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Alysha D. Wira has a total of 3 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Long-interval intracortical inhibition to the biceps brachii is present during arm cycling but is not different than a position–matched tonic contraction

    by Alysha D. Wira, Ibrahim Refai, Evan J. Lockyer, Kevin E. Power

    Previous studies have shown that supraspinal excitability is higher during arm cycling than a position- and intensity-matched tonic contraction, but the underlying mechanisms remain unclear. This study aimed to determine whether long-interval intracortical inhibition (LICI) occurs during arm cycling and if LICI differs between arm cycling and tonic contraction. A paired-pulse transcranial magnetic stimulation (TMS) protocol assessed LICI using a supramaximal conditioning pulse that produced a silent period of approximately 150 ms, followed by a test pulse with a 100 ms interstimulus interval. Stimulation occurred at the 4 o'clock position to align the test pulse with the ascending limb of the biceps brachii electromyography profile during the elbow flexion phase. Additionally, a single-pulse TMS stimulation was delivered 100 ms after the 4 o'clock position. Motor-evoked potentials (MEPs) were measured as ratios: a position-matched ratio of test pulse-evoked MEP over single pulse-evoked MEP. MEP ratios were analyzed for peak-to-peak amplitude during arm cycling and tonic contraction. Results showed that LICI was present during arm cycling ( t(13) = 3.5, p < 0.001, 95% CI [−3.2, −0.75]), but no significant difference in LICI was found between arm cycling and tonic contraction ( t(13) = 1.3, p = 0.242, 95% CI [−0.23, −0.06]). These findings suggest that while LICI is present during arm cycling, it is not task-dependent.