Francesca Romana Rotondo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Francesca Romana Rotondo has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Donatella Capalbo
Department of Mother and Child, University Hospital Federico II, Endo-ERN Center for Rare Endocrine Conditions, 80138 Naples, Italy
1 shared publication - Francesca Cillo
Pediatric Immunology Unit, Department of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy
1 shared publication - Giuliana Giardino
Department of Translational Medical Sciences, Pediatric Section, Federico II University of Naples, Naples, Italy
1 shared publication - Laura Grilli
Pediatric Immunology Unit, Department of Translational Medical Sciences, University of Naples Federico II, 80138 Naples, Italy
1 shared publication - Mariacarolina Salerno
Department of Translational Medical Sciences, Pediatric Endocrinology Unit, University of Naples Federico II
1 shared publication - Roberta Romano
Department of Mother and Child, University Hospital Federico II, ERN-RITA Center for Rare Immundeficiencies, 80138 Naples, Italy
1 shared publication
Latest Publications
- Open Access
The Cross-Knit Between Immune Cells and Thyroid Function in Autoimmune Thyroid Disorders: What We Can Learn from Inborn Errors of Immunity
Autoimmune thyroid diseases (AITDs), including Hashimoto thyroiditis and Graves’ disease, are the most common autoimmune endocrinopathies, affecting up to 5% of the population. Pathogenetic pathways have not yet been fully elucidated, even though different immune-genetic alterations have been proposed. Specific immune defects presenting with AITDs may serve as an experimentum naturae to study the involvement of a specific pathway in the pathogenesis of the disease. In fact, since immune dysregulation with autoimmunity frequently characterize inborn errors of immunity (IEIs), understanding the mechanisms of immune tolerance breakdown leading to autoimmunity in these conditions may provide useful insight to understand the pathogenesis of AITDs. In this review, we will highlight the main immunological aspects of AITDs and their pathogenesis in IEIs.
Open AccessThe Cross-Knit Between Immune Cells and Thyroid Function in Autoimmune Thyroid Disorders: What We Can Learn from Inborn Errors of Immunity
Autoimmune thyroid diseases (AITDs), including Hashimoto thyroiditis and Graves’ disease, are the most common autoimmune endocrinopathies, affecting up to 5% of the population. Pathogenetic pathways have not yet been fully elucidated, even though different immune-genetic alterations have been proposed. Specific immune defects presenting with AITDs may serve as an experimentum naturae to study the involvement of a specific pathway in the pathogenesis of the disease. In fact, since immune dysregulation with autoimmunity frequently characterize inborn errors of immunity (IEIs), understanding the mechanisms of immune tolerance breakdown leading to autoimmunity in these conditions may provide useful insight to understand the pathogenesis of AITDs. In this review, we will highlight the main immunological aspects of AITDs and their pathogenesis in IEIs.