Ursula Mirastschijski
Research Subjects
Ursula Mirastschijski has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Agnieszka Nalewczynska
Estebelle Clinic, Ul Sarmacka 13/129, 02-972 Warszawa, Poland
1 shared publication - Andeera Abu Innab
Dr. Andeera Abu Innab Clinic, Abdoun Al Shamali, Amman 11181, Jordan
1 shared publication - Cosimo Oliva
Obstetrics and Ginecology Unit, San Camillo de Lellis Hospital, 02100 Rieti, Italy
1 shared publication - Dhouha Dridi
Gynecology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico , Milan
1 shared publication - Elena Fasola
Obstetrics and Gynaecology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy
1 shared publication - Eleonora Perrella
Pathology Unit, Campus Bio-Medico University of Rome, 00100 Rome, Italy
1 shared publication
Latest Publications
- Open Access
Low Molecular Weight Hyaluronic Acid Combined with Six Amino Acids for Female Genital Well-Being: A Multicenter Prospective Pilot Study
Genitourinary syndrome of menopause (GSM), which includes vulvovaginal atrophy (VVA) and other bothersome genitourinary symptoms, affects over half of postmenopausal women and has a considerable impact on quality of life. This study aimed to evaluate the efficacy and safety of an injectable combination of hyaluronic acid and amino acids for treating GSM-related symptoms. In this prospective, multicenter study, 84 women aged 46–60 with moderate to severe VVA confirmed by gynecological examination received three intradermal treatments at 21-day intervals, targeting the vestibule, introitus, lower vaginal wall, and labia majora. Symptom severity was assessed using a visual analog scale (VAS), while tolerability and satisfaction were evaluated via a five-point Likert scale. Quality of life was measured using the Satisfaction With Life Scale (SWLS). Assessments were conducted at baseline, after each injection, and at 3- and 6-month follow-up visits. After three months, significant improvements were noted in vaginal dryness, itching, burning, and dyspareunia (all p < 0.001). Patient satisfaction increased from 59.0% to 80.7%, and SWLS scores rose from 4.57 ± 1.76 to 6.53 ± 1.10, reflecting enhanced quality of life. The treatment was well tolerated and demonstrated a favorable safety profile. These findings suggest that this injectable formulation may represent an effective, non-hormonal option for women with VVA, particularly those who are not candidates for hormone therapy.
Open AccessLow Molecular Weight Hyaluronic Acid Combined with Six Amino Acids for Female Genital Well-Being: A Multicenter Prospective Pilot Study
Genitourinary syndrome of menopause (GSM), which includes vulvovaginal atrophy (VVA) and other bothersome genitourinary symptoms, affects over half of postmenopausal women and has a considerable impact on quality of life. This study aimed to evaluate the efficacy and safety of an injectable combination of hyaluronic acid and amino acids for treating GSM-related symptoms. In this prospective, multicenter study, 84 women aged 46–60 with moderate to severe VVA confirmed by gynecological examination received three intradermal treatments at 21-day intervals, targeting the vestibule, introitus, lower vaginal wall, and labia majora. Symptom severity was assessed using a visual analog scale (VAS), while tolerability and satisfaction were evaluated via a five-point Likert scale. Quality of life was measured using the Satisfaction With Life Scale (SWLS). Assessments were conducted at baseline, after each injection, and at 3- and 6-month follow-up visits. After three months, significant improvements were noted in vaginal dryness, itching, burning, and dyspareunia (all p < 0.001). Patient satisfaction increased from 59.0% to 80.7%, and SWLS scores rose from 4.57 ± 1.76 to 6.53 ± 1.10, reflecting enhanced quality of life. The treatment was well tolerated and demonstrated a favorable safety profile. These findings suggest that this injectable formulation may represent an effective, non-hormonal option for women with VVA, particularly those who are not candidates for hormone therapy.