Chiara Mannello
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Chiara Mannello has a total of 13 co-authors. Here are the top co-authors by number of shared publications:
- Alfredo Pontecorvi
Dipartimento di Medicina e chirurgia traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy
1 shared publication - Amato Infante
Advanced Radiology Center (ARC), Department of Oncological Radiotherapy, and Hematology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy
1 shared publication - Antonella Giampietro
Dipartimento di Endocrinologia, Diabetologia e Medicina Interna, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy
1 shared publication - Antonio Bianchi
Facoltà di Medicina e Chirurgia Università Cattolica del Sacro Cuore Rome Italy
1 shared publication - Carmelo Caldarella
UOC di Medicina Nucleare, Dipartimento di Diagnostica per Immagini e Radioterapia Oncologica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS 00168
1 shared publication - Francesco Doglietto
Neurosurgery, Department of Neurosciences, Università Cattolica del Sacro Cuore
1 shared publication
Latest Publications
- Open Access
- 10 February 2026
- Published by MDPI AG in Neuroimaging
- Vol. 1 (1) , 4
Pitfalls in the Diagnosis of Pituitary Germinoma in a Case of Klinefelter Syndrome: Case Report and Literature Review
In this case report, we described the pitfalls in the differential diagnosis of a pituitary stalk lesion in a patient affected by Klinefelter Syndrome (KS) that was initially suspected of infundibulo-neuro-hypophysitis (INH). According to the atypical radiological picture for INH, the not-conclusive pathology findings, and the partial response to glucocorticoid treatment, a [18F] fluorocholine ([18F] FCH) positron emission computed tomography (PET-CT) scan was performed and identified a pituitary stalk proliferative lesion that was suggestive for neoplasia. This clinical case emphasizes the prospective and potential diagnostic role of the [18F] FCH PET-CT in pituitary stalk lesions and in the diagnosis of pituitary germinoma. Our article also includes a brief review of the literature, focusing on the differential diagnosis of lesions involving the pituitary stalk, the oncological risk associated with KS, and the role of nuclear imaging in the evaluation of such cases.
- 10 February 2026
- Published by MDPI AG in Neuroimaging
- Vol. 1 (1) , 4
Open AccessPitfalls in the Diagnosis of Pituitary Germinoma in a Case of Klinefelter Syndrome: Case Report and Literature Review
In this case report, we described the pitfalls in the differential diagnosis of a pituitary stalk lesion in a patient affected by Klinefelter Syndrome (KS) that was initially suspected of infundibulo-neuro-hypophysitis (INH). According to the atypical radiological picture for INH, the not-conclusive pathology findings, and the partial response to glucocorticoid treatment, a [18F] fluorocholine ([18F] FCH) positron emission computed tomography (PET-CT) scan was performed and identified a pituitary stalk proliferative lesion that was suggestive for neoplasia. This clinical case emphasizes the prospective and potential diagnostic role of the [18F] FCH PET-CT in pituitary stalk lesions and in the diagnosis of pituitary germinoma. Our article also includes a brief review of the literature, focusing on the differential diagnosis of lesions involving the pituitary stalk, the oncological risk associated with KS, and the role of nuclear imaging in the evaluation of such cases.