FSFilomeno Coelho da Silva

Filomeno Coelho da Silva

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

The organizations/institutes from the scholar's latest article


Filomeno Coelho da Silva has a total of 7 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Influence of Chlamydia trachomatis Sequence Variation on pgp3 Antigenicity

    by Filomeno Coelho da Silva, Kazutomo Yokoya, Rana Hussain, Gathoni Kamuyu, Anna Godi, Marta Checchi, Tânia de Freitas Raso, Simon Beddows

    Chlamydia trachomatis (Ct) is a sexually transmitted infection (STI) linked to ectopic pregnancy, infertility, invasive lymphogranuloma venereum (LGV), and the blinding disease trachoma. STI, LGV, and trachoma are associated with disease-specific Ct genovars. Serology is an important surveillance tool for estimating exposure, but the impact of genome variation on the antigenicity of Ct proteins is unclear. Two-dimensional antigenicity profiling of Pgp3 antigens representing LGV, STI, and trachoma demonstrated differential antigenicity using antigen-specific murine sera, but geometric distances were not considered significant (≤2-fold) for human infection sera. Pgp3 should be considered a single serotype for the purposes of Ct serosurveillance.