Shuang Yang
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Shuang Yang has a total of 12 co-authors. Here are the top co-authors by number of shared publications:
- Dong Wang
Beijing Anzhen Hospital of Capital Medical University, Beijing 100029, China
1 shared publication - Jiachen Li
Beijing Anzhen Hospital of Capital Medical University, Beijing 100029, China
1 shared publication - Qiang Wang
Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
1 shared publication - Qiang Wang
Beijing Anzhen Hospital of Capital Medical University, Beijing, China.
1 shared publication - Qu Yalun
Beijing Anzhen Hospital, Capital Medical University, Beijing, China
1 shared publication - Xiaoyan Hao
Maternal‐Fetal Medicine Center in Fetal Heart Disease Capital Medical University; Beijing Anzhen Hospital Beijing China
1 shared publication
Latest Publications
- 3 September 2026
- Published by Wiley in Journal of Clinical Ultrasound
Masked ABCA3 ‐Related Interstitial Lung Disease in a Neonate With Prenatally Diagnosed Total Anomalous Pulmonary Venous Connection
Obstructive total anomalous pulmonary venous connection (TAPVC) and ABCA3‐related interstitial lung disease (ILD) rarely coexist. We report a neonate with TAPVC complicated by compound heterozygous ABCA3 variants (c.4180dup/p.V1394fs maternal, c.3446A>G/p.D1149G paternal). Overlapping neonatal respiratory symptoms mask the underlying surfactant disorder, easily causing misdiagnosis and delayed targeted management. This case highlights that the genetic screening for ABCA3 deficiency is mandatory for infants with persistent severe hypoxemia and ventilator dependence after complete TAPVC surgical repair. To our knowledge, this is the first documented co‐occurrence of TAPVC and congenital ABCA3‐related ILD.
- 3 September 2026
- Published by Wiley in Journal of Clinical Ultrasound
Masked ABCA3 ‐Related Interstitial Lung Disease in a Neonate With Prenatally Diagnosed Total Anomalous Pulmonary Venous Connection
Obstructive total anomalous pulmonary venous connection (TAPVC) and ABCA3‐related interstitial lung disease (ILD) rarely coexist. We report a neonate with TAPVC complicated by compound heterozygous ABCA3 variants (c.4180dup/p.V1394fs maternal, c.3446A>G/p.D1149G paternal). Overlapping neonatal respiratory symptoms mask the underlying surfactant disorder, easily causing misdiagnosis and delayed targeted management. This case highlights that the genetic screening for ABCA3 deficiency is mandatory for infants with persistent severe hypoxemia and ventilator dependence after complete TAPVC surgical repair. To our knowledge, this is the first documented co‐occurrence of TAPVC and congenital ABCA3‐related ILD.
- Open Access
- 15 February 2026
- Published by MDPI AG in Journal of Cardiovascular Development and Disease
- Vol. 13 (2) , 95
Echocardiographic Features and Clinical Outcomes of Functional vs. Anatomical Pulmonary Atresia with Intact Ventricular Septum in Neonates
(1) Background: Functional pulmonary atresia (FPA) and pulmonary atresia with intact ventricular septum (PA/IVS) are rare neonatal congenital heart diseases with similar early clinical manifestations but distinct pathophysiology and treatment strategies, making early and accurate differentiation clinically important. (2) Methods: This single-center retrospective study included 43 neonates diagnosed with FPA (n = 12) or PA/IVS (n = 31) between December 2016 and March 2025. Echocardiographic parameters and clinical data were compared between groups, and receiver operating characteristic curve analysis was performed to evaluate the usefulness of selected echocardiographic indices for differentiation in clinical practice. (3) Results: Compared with PA/IVS, neonates with FPA exhibited significantly larger right atrial area, relatively better preserved right ventricular development, larger patent ductus arteriosus diameter, and lower peak tricuspid regurgitation velocity. Several parameters, including right atrial area and the right-to-left ventricular ratio, demonstrated strong between-group discrimination in this cohort. Clinically, most FPA neonates were managed conservatively with favorable outcomes, whereas PA/IVS neonates required surgical intervention and experienced higher perioperative mortality. (4) Conclusions: FPA and PA/IVS differ significantly in right heart morphology, hemodynamic characteristics, and management strategies. A comprehensive multi-parameter echocardiographic evaluation demonstrated discriminatory ability in this cohort, facilitating appropriate treatment decisions and potentially helping to avoid unnecessary high-risk surgical interventions.
- 15 February 2026
- Published by MDPI AG in Journal of Cardiovascular Development and Disease
- Vol. 13 (2) , 95
Open AccessEchocardiographic Features and Clinical Outcomes of Functional vs. Anatomical Pulmonary Atresia with Intact Ventricular Septum in Neonates
(1) Background: Functional pulmonary atresia (FPA) and pulmonary atresia with intact ventricular septum (PA/IVS) are rare neonatal congenital heart diseases with similar early clinical manifestations but distinct pathophysiology and treatment strategies, making early and accurate differentiation clinically important. (2) Methods: This single-center retrospective study included 43 neonates diagnosed with FPA (n = 12) or PA/IVS (n = 31) between December 2016 and March 2025. Echocardiographic parameters and clinical data were compared between groups, and receiver operating characteristic curve analysis was performed to evaluate the usefulness of selected echocardiographic indices for differentiation in clinical practice. (3) Results: Compared with PA/IVS, neonates with FPA exhibited significantly larger right atrial area, relatively better preserved right ventricular development, larger patent ductus arteriosus diameter, and lower peak tricuspid regurgitation velocity. Several parameters, including right atrial area and the right-to-left ventricular ratio, demonstrated strong between-group discrimination in this cohort. Clinically, most FPA neonates were managed conservatively with favorable outcomes, whereas PA/IVS neonates required surgical intervention and experienced higher perioperative mortality. (4) Conclusions: FPA and PA/IVS differ significantly in right heart morphology, hemodynamic characteristics, and management strategies. A comprehensive multi-parameter echocardiographic evaluation demonstrated discriminatory ability in this cohort, facilitating appropriate treatment decisions and potentially helping to avoid unnecessary high-risk surgical interventions.