Current Organizations / Institutes

The organizations/institutes from the scholar's latest article


Ayda Arami has a total of 15 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Comparison of Amplitude‐ and Amplitude‐Frequency‐Modulated Pulses for Outer Volume Suppression in Cardiac MRI : Application to Myocardial T2 Mapping

    by Ayda Arami, Maša Božić‐Iven, Christal van de Steeg‐Henzen, Yidong Zhao, Yi Zhang, Qian Tao, Alexandru Cernicanu, Hildebrandus Johannes Lamb, Sebastian Weingärtner

    Purpose: To evaluate single‐ and dual‐band pulse modules for suppressing extra‐cardiac signal in cardiac MRI, and test their applicability for time‐efficient imaging with reduced FOV in myocardial mapping at 3 T. Methods: Outer Volume Suppression (OVS) was implemented using two regional saturation slabs, along the phase‐encoding direction. Different Amplitude‐Modulated (AM) and Amplitude‐Frequency‐Modulated (AM‐FM) pulses were explored. AM sinc and AM‐FM Hyperbolic Secant (HS) pulses, as single‐ (S:1b and HS:1b) and dual‐band (S:2b and HS:2b) versions, were chosen for full evaluation. Pulses were individually optimized for minimal residual signal and optimal suppression‐band profiles. Pulse performance was assessed through simulations and phantom experiments, and evaluated in seven healthy subjects using residual signal and quantitative myocardial mapping with rFOV. Results: In simulations, optimized HS pulses demonstrated superior suppression‐band profile homogeneity and robustness, while both pulse classes showed comparable sensitivity. Phantom data revealed better signal suppression with HS pulses (S:1b: 19.22% ± 3.23%, S:2b: 16.85% ± 6.80%, HS:1b: 4.66% ± 1.04%, HS:2b: 2.85% ± 1.01%). The residual difference across slabs was slightly reduced using simultaneous dual‐band compared with sequential single‐band approaches (S:1b: 3.81% vs. S:2b: 0.92%; HS:1b: 4.56% vs. HS:2b: 0.66%). In vivo, despite significantly lower residual with HS pulses ( p = 0.0015) and visually observed artifacts with sinc pulses, no significant difference in was observed across all configurations ( p = 0.087) in myocardial mapping. Conclusion: AM‐FM pulses achieved robust suppression of extra‐cardiac signals, with dual‐band implementations minimizing suppression‐band differences. This can enable artifact‐free rFOV imaging, for improved image quality in myocardial mapping.

  • Open Access

    Efficient Interleaved Multi-Band Outer Volume Suppression for Highly Accelerated Simultaneous Multi-Slice Imaging of the Heart

    by Ayda Arami, Omer Burak Demirel, Toygan Kilic, Steen Moeller, Yidong Zhao, Yi Zhang, Qian Tao, Hildo J. Lamb, Mehmet Akçakaya, Sebastian Weingärtner

    In this work, we aimed to develop and evaluate multi-band outer volume suppression pulses for increased acceleration rates in simultaneous multi-slice accelerated cardiac MRI. MB-OVS pulses were constructed from a multi-band combination of two slab-selective saturation pulses and tested for various pulse shapes using Bloch simulation and phantom experiment. The MB-OVS pulses were interleaved between imaging pulses to ensure homogeneous suppression throughout the cardiac cycle/imaging window in vivo. Simultaneous multi-slice (SMS) CINE and first-pass myocardial perfusion scans with and without the proposed MB-OVS pulses were compared in terms of residual artifacts at high acceleration rates. Among the tested pulses, both Bloch simulation and phantom experiments showed that amplitude-optimized sinc pulses provided the best trade-off in suppression efficiency, the required B1+, SAR, and slab profile. CINE imaging with 5-fold SMS-OVS acceleration significantly outperformed imaging without MB-OVS, maintaining leakage-free image quality, even when adding 2-fold in-plane acceleration. SMS-OVS also enabled perfusion imaging in 9 slices with 1.7 × 1.7 mm2 resolution, achieving a 16-fold spatial-only acceleration while ensuring accurate contrast dynamics without leakage artifacts. Interleaved MB-OVS modules enabled thorough leakage artifact suppression in cardiac SMS-accelerated CINE and perfusion imaging, particularly at high acceleration rates. The proposed approach may be promising for unlocking further acceleration potential of SMS in cardiac imaging.