Blanca Molina-Angulo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Blanca Molina-Angulo has a total of 15 co-authors. Here are the top co-authors by number of shared publications:
- Alberto Aragón
Instituto Pluridisciplinar, Complutense University of Madrid, 28040 Madrid, Spain
1 shared publication - Beatriz Vergara Muñoz
Paediatric Oncology and Haematology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
1 shared publication - Carmen Herranz
Department of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain
1 shared publication - Carmen Martin-Fernández
Department of Gastroenterology and Nutrition, Hospital Infantil Universitario Niño Jesús, 28009 Madrid, Spain
1 shared publication - Claudio Alba
Instituto Pluridisciplinar, Complutense University of Madrid, 28040 Madrid, Spain
1 shared publication - Juan Miguel Rodriguez
Instituto Pluridisciplinar, Complutense University of Madrid, 28040 Madrid, Spain
1 shared publication
Latest Publications
- Open Access
- 2 March 2026
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 27 (5) , 2331
Metataxonomic Analysis and Fatty Acid Profiling of Feces from Children Undergoing Hematopoietic Stem Cell Transplantation
Allogeneic hematopoietic stem cell transplantation (HSCT) is a medical procedure to treat hematologic malignancies and restore bone marrow function. However, this approach may lead to graft-versus-host disease (GvHD), a major cause of mortality and morbidity after allogeneic HSCT. Some studies have suggested the involvement of gut microbiota in the development and prognosis of GvHD. In this context, the main objective of this study was to compare the fecal microbiome composition and short-chain profile of pediatric patients who underwent successful HSCT, developed GvHD or died. The bacterial composition was analyzed using 16S rRNA gene sequencing, while short-chain fatty acids (SCFAs) were quantified by gas chromatography. Fecal samples at engraftment were mainly characterized by a loss of bacterial diversity, a depletion of sequences belonging to the genus Blautia and significantly lower concentrations of fecal butyrate and acetate compared with those obtained before HSCT and 100 days after HSCT. Our findings confirm that children experiencing GvHD after HSCT have distinct gut microbiota and SCFA profiles, which might contribute to developing new microbiota-targeted strategies for GvHD prevention during HSCT procedures.
- 2 March 2026
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 27 (5) , 2331
Open AccessMetataxonomic Analysis and Fatty Acid Profiling of Feces from Children Undergoing Hematopoietic Stem Cell Transplantation
Allogeneic hematopoietic stem cell transplantation (HSCT) is a medical procedure to treat hematologic malignancies and restore bone marrow function. However, this approach may lead to graft-versus-host disease (GvHD), a major cause of mortality and morbidity after allogeneic HSCT. Some studies have suggested the involvement of gut microbiota in the development and prognosis of GvHD. In this context, the main objective of this study was to compare the fecal microbiome composition and short-chain profile of pediatric patients who underwent successful HSCT, developed GvHD or died. The bacterial composition was analyzed using 16S rRNA gene sequencing, while short-chain fatty acids (SCFAs) were quantified by gas chromatography. Fecal samples at engraftment were mainly characterized by a loss of bacterial diversity, a depletion of sequences belonging to the genus Blautia and significantly lower concentrations of fecal butyrate and acetate compared with those obtained before HSCT and 100 days after HSCT. Our findings confirm that children experiencing GvHD after HSCT have distinct gut microbiota and SCFA profiles, which might contribute to developing new microbiota-targeted strategies for GvHD prevention during HSCT procedures.