Xiomara Arias
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Xiomara Arias has a total of 32 co-authors. Here are the top co-authors by number of shared publications:
- Adam M. Phillippy
Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health
2 shared publications - Brandon D. Pickett
Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
2 shared publications - Brian P. Walenz
Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
2 shared publications - Brian W. Davis
Department of Veterinary Pathobiology, Texas A&M University, College Station, TX, USA
2 shared publications - Carey Dessaix
School of Biological Sciences, Adelaide University, North Terrace, Adelaide, South Australia, Australia
2 shared publications Christina Sison
2 shared publications
Latest Publications
- Open Access
- 6 August 2026
- Published by Elsevier in Cell Genomics
- Vol. 6 (8)
Phased T2T horse and donkey assemblies from a mule reveal peculiar equid centromere evolution
- 6 August 2026
- Published by Elsevier in Cell Genomics
- Vol. 6 (8)
Open AccessPhased T2T horse and donkey assemblies from a mule reveal peculiar equid centromere evolution
- Open Access
Fully Phased Telomere-to-Telomere Assemblies for Thoroughbred Horse and Donkey Haplotypes derived from a Mule Illuminate the Peculiar Evolution of Equid Centromeres
We present telomere-to-telomere genome assemblies of a Thoroughbred horse and a donkey derived from their mule offspring. Now adopted and annotated by NCBI as reference genomes, these assemblies resolve previously inaccessible regions, including satellite arrays, duplications, and telomeres. Equids are known to exhibit an uncoupling between satellite DNA and centromeric function. The completeness of these assemblies enabled annotation of both satellite-based and satellite-free centromeres, as well as non-centromeric satellite loci, revealing notable centromeric plasticity. They also allowed detailed characterization of the variable binding domains of CENP-A—the epigenetic determinant of centromere identity—and CENP-B, whose association with CENP-A, previously considered typical based on a few model organisms, is absent in equids. Comparative analyses of satellite repeats and centromere positions provide new insights into the accelerated karyotypic reshuffling in equid evolution. These assemblies represent foundational resources for equid genomics and support ongoing initiatives such as the Equine Pangenome Project.
Open AccessFully Phased Telomere-to-Telomere Assemblies for Thoroughbred Horse and Donkey Haplotypes derived from a Mule Illuminate the Peculiar Evolution of Equid Centromeres
We present telomere-to-telomere genome assemblies of a Thoroughbred horse and a donkey derived from their mule offspring. Now adopted and annotated by NCBI as reference genomes, these assemblies resolve previously inaccessible regions, including satellite arrays, duplications, and telomeres. Equids are known to exhibit an uncoupling between satellite DNA and centromeric function. The completeness of these assemblies enabled annotation of both satellite-based and satellite-free centromeres, as well as non-centromeric satellite loci, revealing notable centromeric plasticity. They also allowed detailed characterization of the variable binding domains of CENP-A—the epigenetic determinant of centromere identity—and CENP-B, whose association with CENP-A, previously considered typical based on a few model organisms, is absent in equids. Comparative analyses of satellite repeats and centromere positions provide new insights into the accelerated karyotypic reshuffling in equid evolution. These assemblies represent foundational resources for equid genomics and support ongoing initiatives such as the Equine Pangenome Project.