Wei Chieh Nelson Wee

Background: Generative artificial intelligence (GenAI) is increasingly used to draft multiple-choice questions (MCQs) for health professions education, but much evidence concerns raw model outputs, expert ratings, or item difficulty alone. Educators edit GenAI drafts before use, and whether such items are psychometrically ready for postgraduate assessment remains unclear. Objective: This study aimed to compare human-edited GenAI-assisted and educator-crafted MCQs for postgraduate Family Medicine Applied Knowledge Test–level assessment, examining difficulty, discrimination, reliability, distractor functioning, and participant perceptions. Methods: We conducted a blinded cross-sectional, within-participant comparative psychometric evaluation in Singapore. Sixty best-of-five single-best-answer MCQs were evaluated, 30 human-edited GenAI-assisted items and 30 educator-crafted items, topic-matched across postgraduate FM domains and randomized across 2 assessment sets. Eligible participants were postgraduate doctors enrolled in FM residency or postgraduate family medicine programs, preparing for the Applied Knowledge Test, and blinded to item origin; incomplete paired responses were excluded. Outcomes included paired total scores, score correlation and agreement, Kuder-Richardson Formula 20 reliability, item difficulty index, corrected point-biserial discrimination, distractor functioning, and perceived difficulty, clarity, and relevance. Analyses used paired-sample tests, Pearson correlation, Fisher exact tests, and item-level psychometric statistics, with α=.05 and Bonferroni correction within comparison families. Results: Of 74 participants, 73 completed both item sets and were included in the analysis. The final sample comprised 36 graduate diploma in FM trainees, 5 MMed FM trainees, and 32 FM residents. Paired-sample testing showed lower scores on GenAI-assisted than educator-crafted items (mean 19.12, SD 2.83 vs mean 21.10, SD 3.42 out of 30; mean difference −1.97, 95% CI −2.72 to −1.23; P <.001; Cohen d =0.62), indicating that GenAI-assisted items were not easier. Scores were positively correlated ( r =0.49, 95% CI 0.30‐0.64; P <.001), but Bland-Altman analysis indicated limited agreement. Kuder-Richardson Formula 20 reliability was lower for GenAI-assisted items (0.38 vs 0.60). Mean difficulty index did not differ significantly (0.64 vs 0.70; mean difference −0.07, 95% CI −0.19 to 0.06; P =.29), and more GenAI-assisted items fell within the acceptable difficulty range (18/30, 60.0% vs 13/30, 43.3%). However, mean corrected point-biserial discrimination was lower for GenAI-assisted items (0.09 vs 0.18; mean difference −0.08, 95% CI −0.16 to −0.01; P =.04), and negative discrimination was more common (6/30, 20% vs 3/30, 10%). GenAI-assisted items also had more nonfunctioning and negatively discriminating distractors, although these differences were not statistically significant. Participant ratings of perceived difficulty, clarity, and practice relevance did not differ by origin. Conclusions: Human-edited GenAI-assisted MCQs can achieve plausible difficulty, but difficulty and surface acceptability did not ensure assessment readiness. Using trainee response data, this study extends work on raw outputs or expert opinion. GenAI should be used as a drafting adjunct within educator-led workflows prioritizing key verification, distractor engineering, pilot testing, empirical item analysis, and repair before item-bank or summative use.

BACKGROUND Generative artificial intelligence (GenAI) is increasingly used to draft multiple-choice questions (MCQs) for health professions education, but most evidence has focused on raw AI outputs, expert ratings, or whether AI-generated items are too easy. In practice, educators are more likely to use human-edited GenAI-assisted items. The unresolved question is whether such items are psychometrically ready for assessment use after routine review for clinical accuracy, phrasing, and relevance. OBJECTIVE This study compared human-edited GenAI-assisted and educator-crafted MCQs for postgraduate Family Medicine Applied Knowledge Test (AKT)-level assessment, focusing on difficulty, discrimination, reliability, distractor functioning, and participant post-item ratings. METHODS We conducted a blinded comparative psychometric evaluation of 60 best-of-five single-best-answer MCQs: 30 human-edited GenAI-assisted items and 30 educator-crafted items. Items were topic-matched in pairs and randomised across two assessment sets. Participants were postgraduate doctors preparing for the Family Medicine AKT in Singapore and were blinded to item origin. Outcomes included paired total scores, score correlation and agreement, Kuder-Richardson Formula 20 (KR-20) reliability, item difficulty index, corrected point-biserial discrimination, non-functioning distractors, negatively discriminating distractors, and participant ratings of perceived difficulty, clarity, and relevance. RESULTS Seventy-three participants completed both item sets. Participants scored significantly lower on GenAI-assisted items than educator-crafted items (mean 19.12, SD 2.83 vs mean 21.10, SD 3.42 out of 30; mean difference −1.97, 95% CI −2.72 to −1.23; p<.001; Cohen d=0.62), indicating that GenAI-assisted items were not empirically easier. GenAI-assisted and educator-crafted scores were moderately correlated (r=0.49, p<.001), but agreement was limited. KR-20 reliability was lower for GenAI-assisted than educator-crafted items (0.38 vs 0.60). Mean difficulty index did not differ significantly by item origin (0.64 vs 0.70; p=.290), and more GenAI-assisted items fell within the acceptable difficulty range (18/30, 60.0% vs 13/30, 43.3%). However, GenAI-assisted items showed a weaker discrimination pattern: mean corrected point-biserial correlation was lower (0.09 vs 0.18; p=.036), fewer items achieved good discrimination (2/30, 6.7% vs 4/30, 13.3%), and more had negative discrimination (6/30, 20.0% vs 2/30, 6.7%). Distractor analysis showed more GenAI-assisted items with three or four non-functioning distractors (17/30, 56.7% vs 13/30, 43.3%) and at least one negatively discriminating distractor (14/30, 46.7% vs 9/30, 30.0%), although these differences were not statistically significant. Participant ratings of perceived difficulty, clarity, and relevance did not differ significantly by item origin. CONCLUSIONS Human-edited GenAI-assisted MCQs can achieve plausible postgraduate difficulty, challenging the assumption that such items are necessarily easy. However, difficulty and surface acceptability did not ensure assessment readiness. GenAI-assisted items showed weaker reliability, discrimination, and distractor functioning despite similar participant ratings. GenAI is best positioned as a rapid drafting adjunct within a human-in-the-loop workflow that prioritises key verification, distractor engineering, empirical item analysis, and conservative repair or removal of poorly functioning items before incorporation into question banks or use in.

Background: Obesity is a global public health challenge, with increasing burden especially in emerging Asian economies. While the effectiveness of behavioural interventions for weight management has been extensively studied in the Western Hemisphere, it remains inadequately evaluated in Asian populations. Therefore, we performed a systematic review and meta-analysis to assess the efficacy of behavioural interventions in weight management in Asian adults living with overweight and obesity.Methods: We searched 6 databases and included randomized controlled trials (RCTs) published between 2008 to 2023 which compared behavioural interventions with usual care in Asian adults. We considered 3 adiposity indices: body weight, BMI and waist circumference. We i) conducted meta-analyses using random-effects models; ii) analysed the network of Behaviour Change Techniques (BCT) implemented and iii) performed stratified meta-regressions adjusting for 13 demographic and behavioural factors to identify factors associated with changes in adiposity.Results: Of 25,950 records screened, only 56 RCTs (0·22%, 11,191 participants) were conducted in Asia. The most frequently utilized BCT components were shaping knowledge (19·7%), feedback with monitoring (18·5%), and goals setting with planning (18·1%). Behavioural interventions promoted significant albeit modest improvement across adiposity indices, with reduced weight, BMI and waist circumferences (unadjusted: -2·12 Kg [-2·38; -1·85], -0·81 Kg/m2 [-0·93; -0·68] and -2·63 cm [-3·08; -2·18], respectively). In stratified meta-regressions, behavioural interventions incorporating both diet and physical activity show slightly higher adiposity loss (-3·03 Kg [-4·37; -1·69], -0·92 Kg/m2 [-1·34; -0·51] and -2·28 cm [-3·05; -1·5], respectively).Conclusions: Behavioural interventions in Asian adults living with overweight and obesity were associated with only modest (3-5%) improvements in adiposity. Greater success is linked to combined diet–exercise strategies, and targeted behaviour change techniques. Future research should prioritise culturally tailored, theory-driven interventions that can better meet the unique needs of Asian populations.