JMJoel Mack

Joel Mack

*This is an algorithmically generated author record based on publicly available information.

Joel Mack has a total of 6 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Effect of Target Selection on Mood, Anxiety, Pain, and Medications after Deep Brain Stimulation in Parkinson’s Disease

    by Jocelyn Jiao, Barbara Brumbach, Andrew Ko, Kimmy Su, Yi-Han Lin, Joel Mack, Delaram Safarpour

    Introduction: Pain, anxiety, and mood symptoms are common non-motor manifestations of Parkinson’s disease (PD). Studies demonstrate these non-motor symptoms may improve with DBS, though improvement may differ depending on stimulation target. The objective of this study was to describe the association between medication adjustments with mood, anxiety, and pain symptoms following bilateral STN or GPi DBS in PD. Methods: Thirty-three PD patients undergoing bilateral STN or GPi DBS were prospectively enrolled and followed for 6 months during a three-year period. Data related to medications, mood and anxiety symptoms, and pain assessments were collected at baseline and at multiple time points after surgery. Results: Patients who underwent DBS had significantly lower anxiety scores (Beck Anxiety Inventory; p=0.002) after surgery, compared to baseline. Fluctuation-related pain scores (King’s Parkinson’s Disease Pain Scale; p=0.02) were significantly lower after surgery. Conclusions: Bilateral DBS is associated with greater relief of fluctuation-related pain and decreased anxiety in PD. These findings highlight the need for future research on the impact of non-motor outcomes in ideal DBS target selection for PD patients.

  • Open Access

    Effect of Target Selection on Mood, Anxiety, Pain, and Medications after Deep Brain Stimulation in Parkinson’s Disease

    by Jocelyn Jiao, Barbara Brumbach, Andrew Ko, Kimmy Su, Yi-Han Lin, Joel Mack, Delaram Safarpour

    Introduction:Pain, anxiety, and mood symptoms are common non-motor manifestations of Parkinson’s disease (PD). Studies demonstrate these non-motor symptoms may improve with DBS, though improvement may differ depending on stimulation target. The objective of this study was to describe the association between medication adjustments with mood, anxiety, and pain symptoms following bilateral STN or GPi DBS in PD.Methods:Thirty-three PD patients undergoing bilateral STN or GPi DBS were prospectively enrolled and followed for 6 months during a three-year period. Data related to medications, mood and anxiety symptoms, and pain assessments were collected at baseline and at multiple time points after surgery.Results:Patients who underwent DBS had significantly lower anxiety scores (Beck Anxiety Inventory; p=0.002) after surgery, compared to baseline. Fluctuation-related pain scores (King’s Parkinson’s Disease Pain Scale; p=0.02) were significantly lower after surgery.Conclusions:Bilateral DBS is associated with greater relief of fluctuation-related pain and decreased anxiety in PD. These findings highlight the need for future research on the impact of non-motor outcomes in ideal DBS target selection for PD patients.