Xuanwei Chen
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Xuanwei Chen has a total of 3 co-authors. Here are the top co-authors by number of shared publications:
- Jian Xu
School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University
1 shared publication - Jin Chen
School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou 310053, China
1 shared publication - Yao Zhou
School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China
1 shared publication
Latest Publications
- Open Access
The Impact of Micro/Nanoplastics on Human Hematopoietic Function: Exposure, Deposition, Toxicity, and Mitigation Strategies
The continuous accumulation of micro- and nanoplastics in the human living environment and their deposition in various organs of the body have become a global public health concern with the widespread use of plastic products. This review summarizes the main categories of micro- and nanoplastics entering the body through dietary intake and air inhalation, based on human exposure pathways. By integrating existing literature data, this review estimates the daily intake and excretion of micro- and nanoplastics in humans, summarizes evidence regarding their potential deposition patterns in blood cells and hematopoietic-related organs, mainly inferred from animal and in vitro studies, and discusses the possible impacts of such deposition on hematopoietic function. Furthermore, the toxic effects and potential hazards of micro- and nanoplastics on the human hematopoietic system at both cellular and animal levels, along with the underlying molecular mechanisms, are comprehensively reviewed. From the dual perspectives of environmental governance and bodily protection, exploratory research ideas are proposed, including biodegradation strategies and the application of medicinal and edible homologous substances. This review aims to provide insights for reducing the risk of hematopoietic system diseases and preventing harm caused by micro- and nanoplastics to the human body in the future.
Open AccessThe Impact of Micro/Nanoplastics on Human Hematopoietic Function: Exposure, Deposition, Toxicity, and Mitigation Strategies
The continuous accumulation of micro- and nanoplastics in the human living environment and their deposition in various organs of the body have become a global public health concern with the widespread use of plastic products. This review summarizes the main categories of micro- and nanoplastics entering the body through dietary intake and air inhalation, based on human exposure pathways. By integrating existing literature data, this review estimates the daily intake and excretion of micro- and nanoplastics in humans, summarizes evidence regarding their potential deposition patterns in blood cells and hematopoietic-related organs, mainly inferred from animal and in vitro studies, and discusses the possible impacts of such deposition on hematopoietic function. Furthermore, the toxic effects and potential hazards of micro- and nanoplastics on the human hematopoietic system at both cellular and animal levels, along with the underlying molecular mechanisms, are comprehensively reviewed. From the dual perspectives of environmental governance and bodily protection, exploratory research ideas are proposed, including biodegradation strategies and the application of medicinal and edible homologous substances. This review aims to provide insights for reducing the risk of hematopoietic system diseases and preventing harm caused by micro- and nanoplastics to the human body in the future.