Isaac M. Spiegel
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Isaac M. Spiegel has a total of 47 co-authors. Here are the top co-authors by number of shared publications:
- Ahmet Dogan
Memorial Sloan Kettering Cancer Center, New York, NY
25 shared publications - Alireza Karbalayghareh
Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, USA
25 shared publications - Amos Fong
British Columbia Cancer 6 Vancouver, British Columbia
25 shared publications - Amy Chadburn
Weill Cornell Medicine 13 New York, NY
25 shared publications - Ari M. Melnick
Josep Carreras Leukaemia Research Institute, Barcelona, Spain
25 shared publications - Benedikt W. Pelzer
Weill Cornell Medicine 2 New York City
25 shared publications
Latest Publications
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S4 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutations induce formation of a non-canonical AiBC with MZB features.
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S4 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutations induce formation of a non-canonical AiBC with MZB features.
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S5 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutations lead to increased fitness of female AiBC.
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S5 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutations lead to increased fitness of female AiBC.
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Table 1 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Differentially Expressed Genes per cluster from multiome analysis
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Table 1 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Differentially Expressed Genes per cluster from multiome analysis
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S3 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutations drive an increase in AiBCs
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S3 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutations drive an increase in AiBCs
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Table 2 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
AIBC Signatures used in Fig. 6 H, K and L as well as S6K
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Table 2 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
AIBC Signatures used in Fig. 6 H, K and L as well as S6K
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Table 3 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Gene Overlap used in Fig. 6L and S6K
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Table 3 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Gene Overlap used in Fig. 6L and S6K
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S2 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
SpenLOF and Notch2GOF mutations skew mature B cells towards the MZB compartment
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S2 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
SpenLOF and Notch2GOF mutations skew mature B cells towards the MZB compartment
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Methods 1 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Containing Gating Strategies and Code
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Methods 1 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Containing Gating Strategies and Code
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S1 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
SPENTRUNC mutations with loss of function effects are enriched in DLBCL.
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S1 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
SPENTRUNC mutations with loss of function effects are enriched in DLBCL.
- Open Access
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure S7 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutant lymphomas show signs of XChr dysregulation and TLR pathway dependencies.
- 12 August 2026
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Figure S7 from SPEN Loss Drives Extrafollicular Diffuse Large B-cell Lymphoma with Female-Specific Lethality and Therapeutic Vulnerabilities
Combined SpenLOF and Notch2GOF mutant lymphomas show signs of XChr dysregulation and TLR pathway dependencies.