SLSandreika Osheika Laird

Sandreika Osheika Laird

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

The organizations/institutes from the scholar's latest article


Sandreika Osheika Laird has a total of 11 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Ionic Gelation for Nano-Delivery of Sulforaphane in Animal Feed: A Conceptual Review of Stability, Efficacy, and Translation Potential

    by Kevaun Altamon George Wilson, Mengke Zhang, Yiming Shen, Mukesh Kumar, Sandreika Osheika Laird, Salwa Eman, Jun Xu, Haibing Li, Mengzhi Wang, Xiaodong Guo

    Sulforaphane (SFN), a bioactive compound sourced from cruciferous vegetables, offers significant antioxidant and anti-inflammatory benefits yet its stability in animal feed is a challenge. Nanotechnology-based encapsulation, specifically ionic gelation, has demonstrated efficacy in improving the stability and bioavailability of SFN. This review examines the application of natural polymers such as chitosan and alginate in ionic gelation for the encapsulation of SFN. It also discusses how these polymers can prevent SFN from degrading while traversing the digestive tract. Encapsulation strategies for SFN have been associated with improved bioavailability, with absorption reported in experimental modules, to modulate immune-related and oxidative-stress pathways. However, challenges persist in identifying optimal methods for encapsulating various species, including enhancing encapsulation effectiveness, particle size, and controlled release mechanisms. Additionally, regulatory concerns regarding the safety and environmental impacts of nanoparticles in feed must be addressed. Future research should focus on improving encapsulation techniques and ensuring the safe application of SFN-loaded nanocarriers in livestock feed.

  • Open Access

    Ionic Gelation for Nano-Delivery of Sulforaphane in Animal Feed: A Critical Review of Stability, Efficacy, and Translation Potential

    by Kevaun Wilson, Mengke Zhang, Yiming Shen, Kumar Mukesh, Sandreika Laird, Eman Salwa, Jun Xu, Haibing Li, Mengzhi Wang, Xiaodong Guo

    Sulforaphane (SFN), a bioactive compound sourced from cruciferous vegetables, offers significant antioxidant and anti-inflammatory benefits yet, its stability in animal feed is a challenge. Nanotechnology-based encapsulation, specifically ionic gelation, has demonstrated efficacy in improving the stability and bioavailability of SFN. This review examines the application of natural polymers such as chitosan and alginate in ionic gelation for the encapsulation of SFN. It also discusses how these polymers can prevent SFN from degrading while traversing the digestive tract. Encapsulated SFN has shown enhanced nutritional absorption, elevated immune responses, and reduced oxidative stress in animals. However, challenges persist in identifying optimal methods for encapsulating various species, including enhancing encapsulation effectiveness, particle size, and controlled release mechanisms. Additionally, regulatory concerns regarding the safety and environmental impacts of nanoparticles in feed must be addressed. Future research should focus on improving encapsulation techniques and ensuring the safe application of SFN-loaded nanocarriers in livestock feed.