Noemi Boguslawska
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Noemi Boguslawska has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Alicja Florczak
Division of Anatomy, Department of Human Morphology and Embryology, Wroclaw Medical University, 50368 Wroclaw, Poland
1 shared publication - Barbara Parol
Department and Clinic of Otolaryngology, Wroclaw Medical University, 50556 Wroclaw, Poland
1 shared publication - Grzegorz Ciamciak
Department and Clinic of Otolaryngology, Wroclaw Medical University, 50556 Wroclaw, Poland
1 shared publication - Julia Zapart
Department and Clinic of Otolaryngology, Wroclaw Medical University, 50556 Wroclaw, Poland
1 shared publication - Karolina Dorobisz
Department of Otolaryngology, Wroclaw Medical University, Wroclaw, Poland
1 shared publication - Manuela Makiola
Division of Anatomy, Department of Human Morphology and Embryology, Wroclaw Medical University, 50368 Wroclaw, Poland
1 shared publication
Latest Publications
- Open Access
- 30 April 2026
- Published by MDPI AG in Applied Sciences
- Vol. 16 (9) , 4420
On Molecular Factors in Tympanosclerosis: A Systematic Review with Clinical Implications for Diagnosis and Treatment
Tympanosclerosis is a chronic middle ear disorder characterized by fibrosis, hyalinization, and calcification of the tympanic membrane and ossicles, which often results in conductive hearing loss. The objective of this systematic review was to synthesize current evidence on molecular pathways and genetic susceptibility factors contributing to the development of this condition. PubMed, Embase, Web of Science, and Google Scholar were searched up to December 2024. Eligible studies were original peer-reviewed articles in English investigating gene expression, genetic polymorphisms, or molecular signaling pathways in human or animal models. Risk of bias was assessed using standardized tools, and results were synthesized narratively due to heterogeneity. Twenty-five studies were included from 1815 screened records. Reported findings implicated inflammatory cytokines, such as TNF-α and IL-6, oxidative stress-related enzymes, including CAT, and iNOS, and bone remodeling pathways involving Wnt signaling, TGF-β1, and osteopontin. Polymorphisms in TLR4, NOS2 and NAT2 were associated with increased susceptibility or severity. Evidence remains limited but highlights potential biomarkers and therapeutic targets.
- 30 April 2026
- Published by MDPI AG in Applied Sciences
- Vol. 16 (9) , 4420
Open AccessOn Molecular Factors in Tympanosclerosis: A Systematic Review with Clinical Implications for Diagnosis and Treatment
Tympanosclerosis is a chronic middle ear disorder characterized by fibrosis, hyalinization, and calcification of the tympanic membrane and ossicles, which often results in conductive hearing loss. The objective of this systematic review was to synthesize current evidence on molecular pathways and genetic susceptibility factors contributing to the development of this condition. PubMed, Embase, Web of Science, and Google Scholar were searched up to December 2024. Eligible studies were original peer-reviewed articles in English investigating gene expression, genetic polymorphisms, or molecular signaling pathways in human or animal models. Risk of bias was assessed using standardized tools, and results were synthesized narratively due to heterogeneity. Twenty-five studies were included from 1815 screened records. Reported findings implicated inflammatory cytokines, such as TNF-α and IL-6, oxidative stress-related enzymes, including CAT, and iNOS, and bone remodeling pathways involving Wnt signaling, TGF-β1, and osteopontin. Polymorphisms in TLR4, NOS2 and NAT2 were associated with increased susceptibility or severity. Evidence remains limited but highlights potential biomarkers and therapeutic targets.