Luca Bettazzoni
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Luca Bettazzoni has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Chiara Ambrosi
Department of Primary Health Care, Internal Medicine Unit Addressed to Frailty and Aging, AUSL Romagna, 48100 Ravenna, Italy
1 shared publication - Luca Ielasi
Department of Internal Medicine, Ospedale degli Infermi di Faenza, 48018 Faenza, Italy
1 shared publication - Monica Patrignani
Department of Primary Health Care, Internal Medicine Unit Addressed to Frailty and Aging, AUSL Romagna, 48100 Ravenna, Italy
1 shared publication - Nicola Reggidori
Department of Internal Medicine, Ospedale degli Infermi di Faenza, 48018 Faenza, Italy
1 shared publication - Vittoria Benintende
Department of Primary Health Care, Internal Medicine Unit Addressed to Frailty and Aging, AUSL Romagna, 48100 Ravenna, Italy
1 shared publication
Latest Publications
- Open Access
Clinical Presentation and Therapeutic Approach of Hepatic Sarcoidosis
Sarcoidosis is a multisystemic inflammatory disease defined by non-caseating granuloma formation in involved organs. The liver is the third most implicated organ after the lungs and lymph nodes. Due to its frequently asymptomatic presentation, the true prevalence of hepatic sarcoidosis may be understated. Increased levels of alkaline phosphatase and gamma-glutamyl transferase are the most frequent biochemical abnormalities. The liver biopsy is still the gold standard and reveals non-caseating granulomas in almost all cases. The use of corticosteroids and ursodeoxycholic acid results in a significant decrease in biochemical parameters. However, the clinical course of hepatic sarcoidosis is diverse and requires individualized management strategies, especially to prevent hepatic complications. This review aims to synthesize the current evidence on epidemiology, pathogenesis, diagnostic approaches, and therapeutic strategies for this disease.
Open AccessClinical Presentation and Therapeutic Approach of Hepatic Sarcoidosis
Sarcoidosis is a multisystemic inflammatory disease defined by non-caseating granuloma formation in involved organs. The liver is the third most implicated organ after the lungs and lymph nodes. Due to its frequently asymptomatic presentation, the true prevalence of hepatic sarcoidosis may be understated. Increased levels of alkaline phosphatase and gamma-glutamyl transferase are the most frequent biochemical abnormalities. The liver biopsy is still the gold standard and reveals non-caseating granulomas in almost all cases. The use of corticosteroids and ursodeoxycholic acid results in a significant decrease in biochemical parameters. However, the clinical course of hepatic sarcoidosis is diverse and requires individualized management strategies, especially to prevent hepatic complications. This review aims to synthesize the current evidence on epidemiology, pathogenesis, diagnostic approaches, and therapeutic strategies for this disease.