Michael Z. Mazur
Research Subjects
Michael Z. Mazur has a total of 19 co-authors. Here are the top co-authors by number of shared publications:
- Christian Andres Bermudez
Division of Cardiovascular Surgery, Department of Surgery, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA
2 shared publications - Maria M. Crespo
Hospital of the University of Pennsylvania
2 shared publications - Thomas J. Richards
Division of Pulmonary, Allergy and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
2 shared publications Aly S. Hassaballa
Department of Cardiothoracic Surgery
1 shared publication- Aly Sherif Hassaballa
Ain Shams University Hospitals Cairo Egypt
1 shared publication - Amparo Solé
Division of Pulmonary, Universitat de Valencia, Hospital La Fe, Valencia, Spain
1 shared publication
Latest Publications
- 11 September 2026
- Published by Wolters Kluwer Health in ASAIO Journal
Extracorporeal Membrane Oxygenation Combined With Embolectomy May Yield Better Outcomes Than Extracorporeal Membrane Oxygenation Alone or With Thrombolysis for Acute High-Risk Pulmonary Embolism
Veno-arterial extracorporeal membrane oxygenation (ECMO) is used to support patients with high-risk pulmonary embolism (HR-PE) with cardiogenic shock, but data on mid- and long-term outcomes after reperfusion remain limited. We retrospectively compared outcomes after ECMO with embolectomy, ECMO with thrombolysis, or ECMO alone in patients with HR-PE supported at a tertiary-care hospital (2016–2024). Extracorporeal membrane oxygenation was used in 72 patients with HR-PE; 22 received ECMO with embolectomy, 28 received ECMO with thrombolysis, and 22 received ECMO alone. The median duration of ECMO support was 5 days (interquartile range: 4–6 days). In-hospital complications and support time did not differ significantly between groups. Weaning from ECMO was achieved significantly more often with embolectomy (n = 22, 100%) than with thrombolysis (n = 17, 60.7%) or ECMO alone (n = 8, 36.4%) ( p < 0.01). Survival to hospital discharge was highest after ECMO with embolectomy (n = 18, 81.8%), as compared with ECMO with thrombolysis (n = 16, 57.1%) or ECMO alone (n = 4, 18.1%) ( p < 0.01). One and 3 year survival was 81.8% and 72.7% after ECMO with embolectomy, 55.7% and 46.4% after ECMO with thrombolysis, and 18.2% and 18.2% after ECMO alone ( p < 0.001). Extracorporeal membrane oxygenation with early percutaneous or surgical embolectomy may provide a survival benefit over ECMO alone in patients with HR-PE. Further prospective studies are warranted.
- 11 September 2026
- Published by Wolters Kluwer Health in ASAIO Journal
Extracorporeal Membrane Oxygenation Combined With Embolectomy May Yield Better Outcomes Than Extracorporeal Membrane Oxygenation Alone or With Thrombolysis for Acute High-Risk Pulmonary Embolism
Veno-arterial extracorporeal membrane oxygenation (ECMO) is used to support patients with high-risk pulmonary embolism (HR-PE) with cardiogenic shock, but data on mid- and long-term outcomes after reperfusion remain limited. We retrospectively compared outcomes after ECMO with embolectomy, ECMO with thrombolysis, or ECMO alone in patients with HR-PE supported at a tertiary-care hospital (2016–2024). Extracorporeal membrane oxygenation was used in 72 patients with HR-PE; 22 received ECMO with embolectomy, 28 received ECMO with thrombolysis, and 22 received ECMO alone. The median duration of ECMO support was 5 days (interquartile range: 4–6 days). In-hospital complications and support time did not differ significantly between groups. Weaning from ECMO was achieved significantly more often with embolectomy (n = 22, 100%) than with thrombolysis (n = 17, 60.7%) or ECMO alone (n = 8, 36.4%) ( p < 0.01). Survival to hospital discharge was highest after ECMO with embolectomy (n = 18, 81.8%), as compared with ECMO with thrombolysis (n = 16, 57.1%) or ECMO alone (n = 4, 18.1%) ( p < 0.01). One and 3 year survival was 81.8% and 72.7% after ECMO with embolectomy, 55.7% and 46.4% after ECMO with thrombolysis, and 18.2% and 18.2% after ECMO alone ( p < 0.001). Extracorporeal membrane oxygenation with early percutaneous or surgical embolectomy may provide a survival benefit over ECMO alone in patients with HR-PE. Further prospective studies are warranted.