Azer Karaman
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Azer Karaman has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Aslı Noyan
Hacettepe University Faculty of Medicine
1 shared publication - Deniz Cagdas
Division of Pediatric Immunology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey
1 shared publication - Deniz Ilgun Gurel
Ihsan Dogramaci Children's Hospital, Hacettepe University Faculty of Medicine Ankara Turkey
1 shared publication - Diclehan Orhan
Hacettepe University Faculty of Medicine
1 shared publication - Elif Yüksel
Hacettepe University Faculty of Medicine
1 shared publication - Esra Doymaz
Hacettepe University Faculty of Medicine
1 shared publication
Latest Publications
- 12 June 2026
- Published by SAGE Publications in International Journal of Surgical Pathology
- Vol. 34 (8) , 2085-2091
Synchronous Undifferentiated Embryonal Sarcoma of the Liver and Fibrolamellar Hepatocellular Carcinoma in a Patient with Adenosine Deaminase Deficiency
Adenosine deaminase deficiency causes severe combined immunodeficiency, affecting T and B cells and increasing the risk of infections, immune dysregulation, and malignancy. Undifferentiated embryonal sarcoma of the liver is a rare pediatric mesenchymal tumor. We report a 7-year-old boy with adenosine deaminase deficiency presenting with fever, elevated acute phase reactants, and an 85 × 60 mm 2 heterogeneous cystic liver mass on ultrasonography. Magnetic resonance imaging revealed a second nodule in segments 5 and 6. An abscess was initially suspected, but biopsy confirmed undifferentiated embryonal sarcoma of the liver. After chemotherapy, the patient underwent a left lobectomy and wedge resections. Histology showed complete necrosis of the sarcoma; however, a second tumor—fibrolamellar hepatocellular carcinoma—was identified. While immunodeficiencies are associated with lymphoproliferative disorders and malignancies, the link between adenosine deaminase deficiency and hepatic tumors is unclear. This patient's presentation highlights the potential for multiple primary hepatic malignancies in immunodeficient patients and suggests a need for further investigation.
- 12 June 2026
- Published by SAGE Publications in International Journal of Surgical Pathology
- Vol. 34 (8) , 2085-2091
Synchronous Undifferentiated Embryonal Sarcoma of the Liver and Fibrolamellar Hepatocellular Carcinoma in a Patient with Adenosine Deaminase Deficiency
Adenosine deaminase deficiency causes severe combined immunodeficiency, affecting T and B cells and increasing the risk of infections, immune dysregulation, and malignancy. Undifferentiated embryonal sarcoma of the liver is a rare pediatric mesenchymal tumor. We report a 7-year-old boy with adenosine deaminase deficiency presenting with fever, elevated acute phase reactants, and an 85 × 60 mm 2 heterogeneous cystic liver mass on ultrasonography. Magnetic resonance imaging revealed a second nodule in segments 5 and 6. An abscess was initially suspected, but biopsy confirmed undifferentiated embryonal sarcoma of the liver. After chemotherapy, the patient underwent a left lobectomy and wedge resections. Histology showed complete necrosis of the sarcoma; however, a second tumor—fibrolamellar hepatocellular carcinoma—was identified. While immunodeficiencies are associated with lymphoproliferative disorders and malignancies, the link between adenosine deaminase deficiency and hepatic tumors is unclear. This patient's presentation highlights the potential for multiple primary hepatic malignancies in immunodeficient patients and suggests a need for further investigation.