Daniel Eduardo Gómez-Agredo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Daniel Eduardo Gómez-Agredo has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Alejandro Montoya-Gómez
Grupo de Nutrición, Facultad de Salud, Universidad del Valle, Cali, Colombia
1 shared publication - Eliécer Jiménez-Charris
Grupo de Nutrición, Facultad de Salud, Universidad del Valle, Cali, Colombia
1 shared publication - Gerardo Corzo
Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, UNAM, Apartado Postal 510-3, Cuernavaca, Morelos, 61500, Mexico
1 shared publication - Ibeth Emilse Castiblanco-Mañozca
Grupo de Investigaciones Herpetológicas y Toxinológicas (GIHT), Programa de Biología, Facultad de Ciencias Naturales, Exactas y de la Educación, Universidad del Cauca, Popayán 190002, Colombia
1 shared publication - Javier Hoyos-García
Parque Tecnológico de Innovación del Café y su Caficultura TECNICAFÉ, Venta de Cajibío 190518, Colombia
1 shared publication - Jimmy Alexander Guerrero-Vargas
Grupo de Investigaciones Herpetológicas y Toxinológicas (GIHT), Centro de Investigaciones Biomédicas—Bioterio (CIBUC-Bioterio), Museo de Historia Natural, Departamento de Biología, Facultad de Ciencias Naturales, Exactas y de la Educación, Universidad del Cauca, Popayán 190002, Colombia
1 shared publication
Latest Publications
- Open Access
Antifungal Bioactive Metabolites from the Skin Secretion of Dendropsophus columbianus Against Coffee Rust (Hemileia vastatrix)
Anuran skin secretions are rich sources of bioactive metabolites whose composition may vary according to environmental conditions. In this study, skin secretions from two populations of Dendropsophus columbianus exposed to contrasting environmental conditions (Clarete and Las Guacas, Popayán, Cauca, Colombia) were evaluated for antifungal activity against Hemileia vastatrix, the causal agent of coffee leaf rust. Secretion from the Clarete population showed no significant inhibition of urediniospore germination (p = 0.9999). In contrast, secretion from Las Guacas, a polluted and poorly conserved environment, exhibited significant dose-dependent antifungal activity (p = 0.0004–p < 0.0001). LC-MS analysis detected low-molecular-weight singly charged compounds (400–1500 m/z) consistent with alkaloid-like secondary metabolites. Although no definitive structural identification was achieved, these findings highlight the chemical plasticity and biotechnological potential of D. columbianus for the sustainable control of coffee leaf rust.
Open AccessAntifungal Bioactive Metabolites from the Skin Secretion of Dendropsophus columbianus Against Coffee Rust (Hemileia vastatrix)
Anuran skin secretions are rich sources of bioactive metabolites whose composition may vary according to environmental conditions. In this study, skin secretions from two populations of Dendropsophus columbianus exposed to contrasting environmental conditions (Clarete and Las Guacas, Popayán, Cauca, Colombia) were evaluated for antifungal activity against Hemileia vastatrix, the causal agent of coffee leaf rust. Secretion from the Clarete population showed no significant inhibition of urediniospore germination (p = 0.9999). In contrast, secretion from Las Guacas, a polluted and poorly conserved environment, exhibited significant dose-dependent antifungal activity (p = 0.0004–p < 0.0001). LC-MS analysis detected low-molecular-weight singly charged compounds (400–1500 m/z) consistent with alkaloid-like secondary metabolites. Although no definitive structural identification was achieved, these findings highlight the chemical plasticity and biotechnological potential of D. columbianus for the sustainable control of coffee leaf rust.