Tianen Chen

China Pharmaceutical University

*This is an algorithmically generated author record based on publicly available information.

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China Pharmaceutical University

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Research Interests

Tianen Chen has a total of 11 co-authors. Here are the top co-authors by number of shared publications:

Chengdian Rao
State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China
15 shared publications
Chenxi Wang
State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China
15 shared publications
Kai Zhao
State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China
15 shared publications
Lianbao Kong
The First Affiliated Hospital of Nanjing Medical University
15 shared publications
Lulu Zhang
Department of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, China
15 shared publications
Mingyu Wu
Department of Hepatobiliary Surgery, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China
15 shared publications

Latest Publications

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Open Access
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- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 10 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
A novel combination strategy co-targeting the USP7-FGFR4 axis and standard therapies for HCC.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 10 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
A novel combination strategy co-targeting the USP7-FGFR4 axis and standard therapies for HCC.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 2 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 enhances stemness features and confers resistance to standard therapy in HCC cells in vitro.
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Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 2 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 enhances stemness features and confers resistance to standard therapy in HCC cells in vitro.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 3 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 enhances stemness features and confers resistance to standard therapy in HCC cells in vivo.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 3 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 enhances stemness features and confers resistance to standard therapy in HCC cells in vivo.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 4 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 potentiates tumorgenesis and drug resistance of HCC in both liver-specific SEPTIN7 knockout mice and patient-derived organoids.
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- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 4 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 potentiates tumorgenesis and drug resistance of HCC in both liver-specific SEPTIN7 knockout mice and patient-derived organoids.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 6 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 inhibits K48-linked ubiquitin-mediated proteasomal degradation of FGFR4 by facilitating the recruitment of USP7.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 6 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 inhibits K48-linked ubiquitin-mediated proteasomal degradation of FGFR4 by facilitating the recruitment of USP7.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 5 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 promotes HCC stemness and therapeutic resistance by enhancing the stability and signaling activity of FGFR4.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 5 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 promotes HCC stemness and therapeutic resistance by enhancing the stability and signaling activity of FGFR4.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 8 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 promotes HCC stemness and therapeutic resistance via a RACK1-dependent mechanism, which facilitates FGFR4 phosphorylation at S440 site.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 8 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
SEPTIN7 promotes HCC stemness and therapeutic resistance via a RACK1-dependent mechanism, which facilitates FGFR4 phosphorylation at S440 site.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 7 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
RACK1 facilitates FGFR4 phosphorylation at S440 site.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 7 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
RACK1 facilitates FGFR4 phosphorylation at S440 site.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Figure 9 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
A phosphorylation-dominant and ubiquitination-reinforced mechanism in SEPTIN7-mediated FGFR4 activity.
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Figure 9 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
A phosphorylation-dominant and ubiquitination-reinforced mechanism in SEPTIN7-mediated FGFR4 activity.
Open Access
Website
Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Supplementary Table 1 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
Supplementary Table 1 List of Abbreviations.
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Google Scholar
- 15 September 2026
- Published by American Association for Cancer Research (AACR)
Open Access
Supplementary Table 1 from SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling
by Tifan Sun, Qiruo Sun, Xueyan Zhang, Chenxi Wang, Tianen Chen, Mingyu Wu, Xiao Yang, Chengdian Rao, Yanxu Zhu, Lulu Zhang, et al.
Supplementary Table 1 List of Abbreviations.

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