Alejandra Ortiz-Tirado
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Alejandra Ortiz-Tirado has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Alain Salvador Conejo-Davila
MicroPrime S RL de CV, El colorado, Santiago de Queretaro 76246, Querétaro, Mexico
1 shared publication - Alejandro Vega-Rios
Centro de Investigación en Materiales Avanzados, SC, Miguel de Cervantes #120, Chihuahua 31136, Chihuahua, Mexico
1 shared publication - Ashantha Goonetilleke
Department of Civil Engineering, Birla Institute of Technology and Science, Pilani Campus, Vidya Vihar, Pilani 333031, Rajasthan, India
1 shared publication - Erick Roberto Bandala
NanRenewables LLC, 100 Seapoint Blv. Bldg 5, Savannah, GA 31404, USA
1 shared publication - James M. McGree
School of Mathematical Sciences, Queensland University of Technology, GPO Box 2344, Brisbane, QLD 4001, Australia
1 shared publication - Luis Fernando Mejia Diaz
Transdisciplinary Institute of Research and Services (ITRANS), University of Guadalajara, Zapopan 45150, Jalisco, Mexico
1 shared publication
Latest Publications
- Open Access
Fungal-Based Biogenic Silver Nanoparticles: Synthesis, Mathematical Modeling and Application
Biogenic synthesis based on microorganisms and plants utilizes biomolecules and metabolites that act as reducing and stabilizing agents. Furthermore, these biomolecules confer enhanced properties, increasing their effectiveness as antibacterial agents, even against multidrug-resistant bacteria. However, there is currently a lack of knowledge regarding the characteristics of the biomolecules involved and their mechanisms during synthesis, which limits their wider application. This research study focused on the synthesis of AgNPs using extracellularly secreted biomolecules from the filamentous fungus R. stolonifer. The results indicated that the concentration of the biomolecules depends on the response of the fungus to specific operational conditions. Furthermore, a relationship was found between the concentrations of total proteins and polyphenols, an optimal protein-to-polyphenol ratio, and the formation of AgNPs. Characterization of the fungus extracts revealed a complex mixture of over 100 metabolites, primarily phenolic compounds, proteins, and methoxylated compounds, thereby identifying a synergistic mechanism that enables the reduction and stabilization of AgNPs. Disinfection tests confirmed the antibacterial efficacy of all biosynthesized AgNPs, achieving 100% elimination of Escherichia coli and Staphylococcus aureus. The study outcomes highlight the important role of fungal biomolecules for creating a sustainable and efficient method for synthesizing antimicrobial nanoparticles with high efficacy for disinfectant applications.
Open AccessFungal-Based Biogenic Silver Nanoparticles: Synthesis, Mathematical Modeling and Application
Biogenic synthesis based on microorganisms and plants utilizes biomolecules and metabolites that act as reducing and stabilizing agents. Furthermore, these biomolecules confer enhanced properties, increasing their effectiveness as antibacterial agents, even against multidrug-resistant bacteria. However, there is currently a lack of knowledge regarding the characteristics of the biomolecules involved and their mechanisms during synthesis, which limits their wider application. This research study focused on the synthesis of AgNPs using extracellularly secreted biomolecules from the filamentous fungus R. stolonifer. The results indicated that the concentration of the biomolecules depends on the response of the fungus to specific operational conditions. Furthermore, a relationship was found between the concentrations of total proteins and polyphenols, an optimal protein-to-polyphenol ratio, and the formation of AgNPs. Characterization of the fungus extracts revealed a complex mixture of over 100 metabolites, primarily phenolic compounds, proteins, and methoxylated compounds, thereby identifying a synergistic mechanism that enables the reduction and stabilization of AgNPs. Disinfection tests confirmed the antibacterial efficacy of all biosynthesized AgNPs, achieving 100% elimination of Escherichia coli and Staphylococcus aureus. The study outcomes highlight the important role of fungal biomolecules for creating a sustainable and efficient method for synthesizing antimicrobial nanoparticles with high efficacy for disinfectant applications.