On the Formation and Effects of Thromboxane A2 in Human Platelets
Authors:
- 1 November 1976
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 98 (3) , 285-294
Abstract
Incubation of arachidonic acid and prostaglandin G2 with a suspension of human platelets led to formation of an unstable (t1/2 41 ± 7 s) compound, thromboxane A2 Thromboxane A2 induced irreversible aggregation of washed platelets and of platelets in platelet‐rich plasma and caused release of serotonin and ADP from platelets in platelet‐rich plasma.Keywords
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