Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy
Authors:
- 1 February 2022
- journal article
- research article
- Published by Elsevier in Free Radical Biology and Medicine
- Vol. 179, 76-94
Abstract
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This publication has 50 references indexed in Scilit:
- Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 CellsInternational Journal of Molecular Sciences, 2013
- Review: Microglia in protein aggregation disorders: friend or foe?Neuropathology and Applied Neurobiology, 2013
- Xanthones from Polygala karensium inhibit neuraminidases from influenza A virusesBioorganic & Medicinal Chemistry Letters, 2012
- Signaling by ROS drives inflammasome activationEuropean Journal of Immunology, 2010
- Neuronal cell death in neurodegenerative diseases: recurring themes around protein handlingJournal of Cellular and Molecular Medicine, 2008
- Autophagy: process and functionGenes & Development, 2007
- SHP-2 Regulates Cell Growth by Controlling the mTOR/S6 Kinase 1 PathwayJournal of Biological Chemistry, 2007
- SHP-2 Phosphatase Negatively Regulates the TRIF Adaptor Protein-Dependent Type I Interferon and Proinflammatory Cytokine ProductionImmunity, 2006
- Raft-mediated Src Homology 2 Domain-containing Proteintyrosine Phosphatase 2 (SHP-2) Regulation in MicrogliaJournal of Biological Chemistry, 2006
- The SHP-2 tyrosine phosphatase: Signaling mechanisms and biological functionsCell Research, 2000