Diethylzinc-Mediated Metalloamination–Alkylation of N,N-Dimethylhydrazinoalkenes. Catalysis of C–Zn Alkylation Using Simple Cu(I) Salts
Authors:
- 12 October 2017
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 29 (02) , 181-184
Abstract
This manuscript is dedicated to Professor Albert Padwa on the occasion of his 80th birthday Metalloamination–alkylation of representative N,N-dimethylhydrazinoalkenes has been shown to be effectively catalyzed by CuBr·SMe2, CuCN, and CuI. The current method obviates the use of stoichiometric CuCN(LiCl)2 as a promoter for the electrophilic functionalization event.Keywords
Funding Information
- National Institute of General Medical Sciences (GM116949)
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