Peroxiredoxin 6 Overexpression Induces Anxiolytic and Depression-Like Behaviors by Regulating the Serotonergic Pathway in Mice
Open Access
- 31 March 2022
- journal article
- research article
- Published by The Korean Society of Applied Pharmacology in Biomolecules & Therapeutics
- Vol. 30 (4) , 334-339
Abstract
Sun Mi Gu, Eunhye Yu, Young Eun Kim, Seong Shoon Yoon, Dohyun Lee, Jin Tae Hong and Jaesuk Yun. Biomolecules & Therapeutics 2022;30:334-9. https://doi.org/10.4062/biomolther.2021.169Keywords
Funding Information
- National Research Foundation of Korea (2017R1A5A2015541, NRF-2021R1I1A1A01058188)
- Ministry of Education (2021RIS-001, NRF-2021R1I1A1A01058188)
- Ministry of Food and Drug Safety (20182MFDS422, 20182MFDS425)
- Ministry of Science and ICT, South Korea (2017R1A5A2015541)
This publication has 39 references indexed in Scilit:
- The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2 Arg 439 His knockin mousePhilosophical Transactions of the Royal Society B: Biological Sciences, 2012
- New Horizons for Selective 5-HT2C Receptor Ligands in Psychiatric/Neurological DisordersNeuropsychopharmacology, 2010
- The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogenPsychopharmacology, 2010
- Effect of high intratesticular estrogen on global gene expression and testicular cell number in ratsReproductive Biology and Endocrinology, 2010
- Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming testsNature Genetics, 2009
- Association of Major Depressive Disorder with Serum Myeloperoxidase and Other Markers of Inflammation: A Twin StudyBiological Psychiatry, 2008
- Hypofunctional glutamatergic neurotransmission in the prefrontal cortex is involved in the emotional deficit induced by repeated treatment with phencyclidine in mice: Implications for abnormalities of glutamate release and NMDA–CaMKII signalingBehavioural Brain Research, 2007
- Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypesMolecular Psychiatry, 2006
- Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertralineLife Sciences, 1996
- Depression: a new animal model sensitive to antidepressant treatmentsNature, 1977