Trans-11 vaccenic acid improves glucose homeostasis in a model of type 2 diabetes by promoting insulin secretion via GPR40
Authors:
- Xiaofeng WangXWXiaofeng Wang
- Alexandra EnglandAEAlexandra England
- Charlene SinclairCSCharlene Sinclair
- Frances MerkoskyFMFrances Merkosky
- Catherine B. ChanCatherine B. Chan
- 1 September 2019
- journal article
- research article
- Published by Elsevier in Journal of Functional Foods
- Vol. 60, 103410
Abstract
No abstract availableKeywords
Funding Information
- Dairy Farmers of Canada
This publication has 31 references indexed in Scilit:
- Dairy Products Consumption and Risk of Type 2 Diabetes: Systematic Review and Dose-Response Meta-AnalysisPLOS ONE, 2013
- TAK-875, an Orally Available G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonist, Enhances Glucose-Dependent Insulin Secretion and Improves Both Postprandial and Fasting Hyperglycemia in Type 2 Diabetic RatsThe Journal of Pharmacology and Experimental Therapeutics, 2011
- Human health benefits of vaccenic acidApplied Physiology, Nutrition, and Metabolism, 2009
- Mechanisms of biphasic insulin-granule exocytosis – roles of the cytoskeleton, small GTPases and SNARE proteinsJournal of Cell Science, 2009
- Gpr40 Is Expressed in Enteroendocrine Cells and Mediates Free Fatty Acid Stimulation of Incretin SecretionDiabetes, 2008
- Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40Molecular and Cellular Endocrinology, 2007
- The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty AcidsJournal of Biological Chemistry, 2003
- Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40Nature, 2003
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001
- Effect of pertussis toxin on islet insulin secretion in obese (fa/fa) Zucker ratsMolecular and Cellular Endocrinology, 1991