UCH-L1 down-regulates HER2 expression and increases lapatinib sensitivity by interacting with HSP90 in HER2-positive breast cancer
Open Access
- 1 July 2026
- journal article
- Published by KEAI Publishing in Genes & Diseases
- Vol. 13 (4) , 101952
Abstract
No abstract availableFunding Information
- National Natural Science Foundation of China (82430084)
- National Natural Science Foundation of China (U2102203)
- National Natural Science Foundation of China (82372712)
- Henan Provincial Science and Technology Research Project (242102311027)
- National Key Research and Development Program of China (2023ZD0502200)
- National Key Research and Development Program of China (2020YFA0112300)
- Chongqing Medical University
This publication has 5 references indexed in Scilit:
- Ubiquitin C‑terminal hydrolase‑L1: A new cancer marker and therapeutic target with dual effects (Review)Oncology Letters, 2023
- Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer MetastasisClinical Cancer Research, 2020
- UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast CancerTheranostics, 2020
- Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian CancerScience, 1989
- THE IMMUNOLOCALIZATION OF PROTEIN GENE-PRODUCT 9.5 USING RABBIT POLYCLONAL AND MOUSE MONOCLONAL-ANTIBODIES1988