Limited Periods of Gene Expression in Immunoglobulin-Synthesizing Cells
Authors:
- 27 June 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 164 (3887) , 1524-1525
Abstract
In synchronized human lymphoid cell lines, production of immunoglobulins G and M is greatest during the late G1 and S phases of the cell cycle. Little immunoglobulin appears immediately before, during, and immediately after mitosis. The results indicate that transcription of immunoglobulin genes takes place during a limited part of the mitotic cycle.Keywords
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