Novel reactions involved in energy conservation by methanogenic archaea

Authors:
Publisher website
Google Scholar
Abstract
Methanogenic archaea of the order Methanosarcinales which utilize C1 compounds such as methanol, methylamines or H2+CO2, employ two novel membrane‐bound electron transport systems generating an electrochemical proton gradient: the H2:heterodisulfide oxidoreductase and the F420H2:heterodisulfide oxidoreductase. The systems are composed of the heterodisulfide reductase and either a membrane‐bound hydrogenase or a F420H2 dehydrogenase which is functionally homologous to the proton‐translocating NADH dehydrogenase. Cytochromes and the novel electron carrier methanophenazine are also involved. In addition, the methyl‐H4MPT:HS‐CoM methyltransferase is bioenergetically relevant. The enzyme couples methyl group transfer with the translocation of sodium ions and seems to be present in all methanogens. The proton‐translocating systems with the participation of cytochromes and methanophenazine have been found so far only in the Methanosarcinales.

This publication has 47 references indexed in Scilit: