The ADP-ribosylating thermozyme from Sulfolobus solfataricus is a DING protein
- 13 November 2008
- journal article
- Published by Walter de Gruyter GmbH in Biological Chemistry
- Vol. 390 (1) , 27-30
Abstract
The partial amino acid sequence of the sulfolobal thermoprotein biochemically characterized as poly(ADP-ribose)polymerase-like enzyme overlaps those of DING proteins. This group of proteins, widely occurring in animals, plants and eubacteria, shows a characteristic and highly conserved N-terminus, DINGGGATL. The sequence of the N-terminal region and of the analyzed tryptic peptides of the sulfolobal thermozyme shows a high similarity with most of the DING proteins from databases. This is the first example of a DING protein from a sulfolobal source.Keywords
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