Dentifrices for preventing erosive tooth wear: An in vitro comparative study

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Abstract
Erosive tooth wear is a progressive condition that compromises enamel structure and requires preventive strategies. This in vitro study aimed to compare the protective effects of fluoride‐based dentifrices containing various bioactive agents on sound enamel subjected to simulated erosive–abrasive challenges. Sixty bovine enamel blocks were randomly assigned to five dentifrices containing: bioactive silica + 1100 ppm F − from sodium fluoride (BAS/NaF), 0.454% stannous fluoride (SnF), sodium‐calcium phosphosilicate + 1426 ppm F − from sodium fluoride (SCP/NaF), 1100 ppm F − from sodium fluoride (NaF), and a fluoride‐free (FF) control. Specimens underwent 7 days of pH cycling, including three daily acid challenges and 2‐min immersion in dentifrice slurries including 15 s brushing. Measurements included surface microhardness, surface roughness, fluorescence loss, and surface loss. Between‐group differences were assessed using one‐way anova with Tukey post hoc tests. The BAS/NaF and SnF dentifrices outperformed the other formulations, maintaining higher surface hardness and lower surface loss and fluorescence loss ( p < 0.05). The NaF and the SCP/NaF dentifrices showed intermediate results. The fluoride‐free dentifrice exhibited the highest mineral loss. Dentifrices combining fluoride with bioactive ingredients enhanced enamel resistance to erosive–abrasive challenges, with bioactive silica and stannous fluoride showing the strongest effects.

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