Two populations of Ia-like molecules on a human B cell line.
Authors:
Open Access
- 1 July 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 125 (1) , 293-299
Abstract
Evidence is presented for two populations of Ia-like molecules on the human B cell line Raji. Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic determinants on B cell antigens. Both immunoprecipitate 34,000- and 28,000-dalton material from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well. Immunodepletion experiments confirm that the antibodies react with two different populations of molecules.Keywords
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