An efficient synthesis of novel spiroindenopyridazine-4 H -pyran derivatives
- 10 November 2017
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in New Journal of Chemistry
- Vol. 41 (24) , 14954-14959
Abstract
A convenient one-pot protocol was developed for the synthesis of spiro[indeno[2,1-c]pyridazine-9,4′-pyran]-3′,4-dicarbonitrile derivatives by the reaction of cyanoacetohydrazide, ninhydrin, malononitrile and various cyclic CH-acids under reflux condition in ethanol. No hazardous solvent or catalyst was used in this method. The main advantages of this procedure are the availability of starting materials, very high yields and easy purification.Keywords
Funding Information
- Imam Khomeini International University
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