Dideoxyinosine in Children with Symptomatic Human Immunodeficiency Virus Infection
Authors:
- Robert N. HussonRHRobert N. Husson
- Frank M. BalisFBFrank M. Balis
- Pim BrouwersPBPim Brouwers
- Janie EddyJEJanie Eddy
- Deborah El-AminDEDeborah El-Amin
- Janet GressJGJanet Gress
- Mary HawkinsMHMary Hawkins
- Paul JarosinskiPJPaul Jarosinski
- Howard MossHMHoward Moss
- David PoplackDPDavid Poplack
- Sheila SantacroceSSSheila Santacroce
- 17 January 1991
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 324 (3) , 137-144
Abstract
2′,3′-Dideoxyinosine (ddI) is a dideoxynucleoside with potent activity in vitro against the human immunodeficiency virus (HIV). In initial clinical trials in adults, ddI showed evidence of antiretroviral activity with little hematologic toxicity.Keywords
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